PubMed Health⌕ Search

Biomedical subjects

K Kuszewski

Publications and source records attributed to K Kuszewski.

18 recordsLinked to original sources
PubMed2001

[Hepatitis B in Poland in 1999].

A total of 3,508 of hepatitis B cases (including 152 cases of mixed HBV and HCV infections) were reported in Poland in 1999. For the first time since 1979, when registration has began, the incidence decreased below 10.0 and was 9.1 per 100,000. The program of eradication of hepatitis B in Poland has been introduced in 1993 and since then the fourfold decrease in number of hepatitis B cases has been noticed. During the past 7 years there has been a steady decline in hepatitis B incidence. In 1997 the incidence decreased 23% as compared to 1996, followed by 16.8% decrease in 1998 and 13.9% in 1999; the marked differences in incidence in particular voivodeships have been observed. The overall rate of hospitalized hepatitis B cases in Poland reached 98.1%. A total of 25 cases of hepatitis B (rate 1.2 per 100,000) occurred among children under 4 years of age, who should be vaccinated. Among children aged 5-9 years, of which many could not be vaccinated, the incidence rate was 6 times higher, ranging from 4.9 per 100,000 in girls to 9.8 per 100,000 in boys. The increase of incidence from 5.3 to 9.2 was observed in young people (14-24 years old). Data from the study of serological markers of hepatitis B, conducted among 4,500 health care workers during 1998-2000, have indicated that about 22% of health care workers have been infected with HBV (in 21% of persons anti-HBc and in 1% anti-HBc together with HBsAg were detected).

Adolescent↗
PubMed2001

[Hepatitis C in Poland 1999].

In 1999, a total of 1,988 (5.1 per 100,000) acute and chronic hepatitis C cases were noted. HCV and HBV coinfections accounted for 7.6% reported cases. Incidence in urban areas (6.9 per 100,000) was 200% those in rural areas (2.3 per 100,000). Incidence among men (6.0 per 100,000) was 40% those among women (4.3 per 100,000). The most predominant groups were age 40-44 (235 cases, 11.8%) and 65-74 (229 cases, 11.5%). Presented data should be taken cautiously because of development of diagnosis and reporting.

Adolescent↗
PubMed2001

[Influenza in Poland in 1999].

A total of 2,344,773 cases of influenza were reported in Poland in 1999, corresponding to 6066.1 cases per 100,000 population and was 2.8 times higher as compared with 1998. The highest influenza incidence rate (10,770.9 per 100,000) was reported in Małopolskie voivodeship. Children up to 14 years old accounted for 34.9% (818,629; incidence 10,616.2 per 100,000) of all reported influenza cases. A total of 3,925 persons required hospitalization, eight times more as compared with 1998. The number of deaths due to influenza amounted to 402. Compared with 1998, in 1999 reported influenza deaths increased 6.4 times. During the second two weeks of January 1999 four influenza strains of type B were isolated from patients aged 13, 16, 31, and 38. During the first part of February 1999 another two strains of influenza virus type B were obtained from persons aged 35 and 45. All six isolates were related antigenically to the vaccine strain B/Beijing/184/93 and were confirmed by the WHO Collaborating Center for Influenza Reference and Research, London.

Adolescent↗
PubMed2000

The epidemiology and history of influenza.

Disease caused by influenza virus has been known from ancient times. However, in spite of the progress in pharmacology and vaccinology, this pathogen still affects morbidity and mortality in all age groups all over the world. This article gives some essential information on the history of influenza, its pandemics and main features of influenza viruses. Data on the epidemiologic situation of influenza in Poland in the period 1946-1999 are presented. Influenza surveillance issues and particularly prevention of influenza by vaccinations are discussed.

Humans↗
PubMed2000

[Influenza in 1998].

In Poland in 1998 total number of 825,345 cases of influenza were noted. It meant decrease in half (47.7%) of the number of cases registered in 1997. Cumulative incidence was 2134.5 per 100,000. It was 449,592 cases in children up to 14 years old. 489 persons were hospitalized which was 0.06% of reported cases. Percentage of hospitalizations decreased almost in half. Number of case fatalities due to influenza was 63. In January 1998 there were isolated four variants of Influenza virus of subtype A(H3N2). They were related to the variant included in the influenza vaccine used in epidemic season 1997/1998 (results of antigenic analysis was confirmed by WHO Collaborating Centre for Influenza Reference and Research, London).

Adolescent↗
PubMed2000

[Hepatitis B in 1998].

In 1998 in Poland 4074 new cases of viral hepatitis B were noted (including 149 mixed infections with HBV and HCV). Incidence was 10.5 per 100,000 and it was 2.2 lower than year ago. In 1997 the infection with HBV was observed in 4896 persons, including 66 mixed infections (incidence rate 12.7/100,000). Constant decrease in number of new cases and incidence was observed in both sexes gender and all age groups after introduction of the intensive program of prevention and control of hepatitis B in 1993. It lead to almost 4 fold decrease of the number of new cases. There are still significant differences in incidence between particular voivodeships. For example between voivodeships Lodz and Warsaw the difference is twofold (20.6 and 10.2). The incidence of hepatitis B is still higher in cities (11.8) then in rural areas (8.6). It is dependent on gender and age. The lowest incidence is among children 0-4 years old 2.8/100,000 (61 cases). Twofold increase of incidence (from 4.6 to 9.8) is observed between ages 14 and 24; it is mainly due to higher incidence among young men especially those living in cities.

Adolescent↗
PubMed2000

[Hepatitis C in 1998].

In 1998, 1,710 cases of viral hepatitis type C were reported (incidence 4.4 per 100,000). There were 149 (8.7%) mixed infections: HCV + BBV. Both acute cases and newly diagnosed chronic cases were registered. Highest incidence was found in people 55-59 years old (7.49) and 60-64 years old (7.05). Cumulative incidence was higher in men (5.2), than in women (3.7). In particular in age groups of 15-34 incidence in men was even 2-3 times higher that in women. Incidence in cities (5.9) was 3 times higher then in rural areas (2.0). Among reported cases at least 113 (6.6%) employees of health system were found. Data presented above should be taken cautiously because separate registration of hepatitis C was introduced in Poland as late as in 1997.

Female↗
PubMed1999

[Influenza in 1997].

The number of cases of influenza and influenza-like illness registered in Poland in 1997 amounted to 1,578,494. This number of cases is 41.8% lower when compared with the previous year 1996. The incidence of influenza amounted to 4,084 per 100,000 inhabitants. The number of influenza cases registered in children aged up to 14 years was 557,033. This is 35.6% of total number of cases. The incidence of influenza in this group amounted to 6,828.7 per 100,000 and was 67% higher than total incidence. In the beginning of January 1997 six strains of A (H3N2) influenza virus were isolated in the National Influenza Center WHO, Dept. of Virology, National Institute of Hygiene. These isolates were similar to A/Wuhan/359/95 and A/Johannesburg/33/94 strains and were obtained from patients aged 5, 6, 45, 50, 75 and 85 living in Warsaw. In February 1997 next six strains A (H3N2) similar to A/Wuhan/359/95 were isolated. Four of them were obtained from patients aged 9, 10, 11 and 14 living in Lublin. One strain was isolated from patient aged 14 living in Kielce and the last one was obtained from patient aged 70 from Warsaw. In general, ten strains isolated in 1997 were similar to the vaccine strain A/Wuhan/359/95 recommended for the epidemic season 1996/97, while two isolates were antigenically similar to the strain included in the vaccine in the previous epidemic season, i.e. 1995/96.

Adolescent↗
PubMed1999

[Hepatitis B and C in 1997].

In 1997, 4,896 cases of hepatitis B were notified in Poland, including 66 mixed infections with B and C virus. The number of cases notified was 1,539 less than in 1996. The incidence rate was 12.7/100,000, which was lower by 4.0 than in the proceeding year (16.7), what means a decline in the incidence rate of hepatitis B by 24%. 1997 was the fifth consecutive year when a decline in incidence rate hepatitis B was observed, since the intensive program of hepatitis B prevention was introduced in 1993 Hepatitis B incidence rate was greater in urban areas (14.1/100,000) than in villages (10.4/100,000). In urban area, the incidence rate was proportional to the number of habitants (fig. 1). The immunisation programme is the main reason of falling incidence among children aged 0-3. In 1997, 36 cases were notified in children aged 0-3 while in 1990 129 cases were registered. The incidence rate has fallen from 9.5/100,000 to 2.5/100,000 in this age group, which means a drop of 74%. The analysis of notified cases shows that the program of hepatitis B prevention is effective. Positive trends from previous years were maintained in 1997 although the declining trend has been slightly sloved. In 1997 hepatitis C has become a statuatory notificable disease in Poland. 1,064 cases were notified, with an overall incidence of 2.75/100,000.

Adolescent↗
PubMed1993

[Epidemiologic situation of diphtheria in the European region of the World Health Organization in 1992 and during the first half of 1993].

In sixties and seventies small number of diphtheria cases was registered in European countries and diphtheria seems to go to be eliminated. Between 1982 and 1985 the first wave of diphtheria epidemic, and since 1990 the second wave were observes. Majority of cases during the first epidemic was registered in Soviet Union, but also in Germany, Italy, Portugal, Turkey and Sweden. Since 1990 increasing numbers of cases were registered in Russia and Ukraine. Some imported cases from these countries were observed in Bielorussia, Lithuania, Latvia, Estonia, Poland, Finland, Norway. Prophylactic measures undertaken in Russia and Ukraine were not sufficient. Shortage of vaccines were the most important reason of this situation. In 1992 one case and in first six months of 1993 five cases of diphtheria were imported in Poland. Production of Td vaccine started in Poland in 1991 and vaccination of adolescents in 19 as well as vaccination of some risk groups were introduced especially in the east port of country.

Adolescent↗
PubMed1993

[Evaluation of immunologic response in individuals of various ages to Td vaccine].

Forty adults volunteers 25-65 years received 10 BU tetanus and 2 Lf diphtheria adsorbed vaccine (Td). The tolerance was very good, it was not depended on the age antitoxin level. Eleven persons have not diphtheria immunity before the vaccination. The serological response was determined by the passive hemagglutination in sera collected in 4 week after the vaccination. Only in one serum the level of diphtheria antitoxin was below 0.1 IU/ml. It is recommended than two doses of Td vaccine are necessary for anyone whose last dose of diphtheria anatoxin was given more than 10 years ago especially to persons travelling to other countries at risk for diphtheria.

Adult↗
PubMed1992

[Evaluation of vaccination reactions and serologic responses after Td vaccine in pilot studies].

Fifty six young adults volunteers received 10 BU tetanus and 2 Lf Diphtheria adsorbed vaccine (Td). Reactogenicity was noted in the special formulas, the serological response was determined by the passive hemagglutination in sera collected before and in 4 week after the vaccination. Twelve persons were not immunity for diphtheria before booster. The results confirmed the safety and efficacy of the polish Td vaccine.

Adult↗