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Biomedical subjects

K L Egan

Publications and source records attributed to K L Egan.

5 recordsLinked to original sources
PubMed1997

Environmental equity in Superfund. Demographics of the discovery and prioritization of abandoned toxic sites.

This article presents findings of the first national tract-level analysis of the distribution of residential characteristics, including the percentage of selected minorities and socioeconomically disadvantaged groups, in relation to uncontrolled toxic waste sites (i.e., CERCLIS and NPL sites). In contrast to prevailing notions, the authors find that uncontrolled toxic waste sites are not disproportionately located in minority neighborhoods or neighborhoods of socioeconomically disadvantaged residents. However, multivariate analyses of site distribution and a hazard regression analysis of the site prioritization process suggest that communities with a higher percentage of Black residents are less likely to receive NPL (National Priorities List) designation, delaying potential remediation. Biases in the prioritization process are, however, substantively small.

Censuses↗
PubMed1984

Detection of breast carcinoma: comparison of automated water-path whole-breast sonography, mammography, and physical examination.

A comparative study of independently conducted physical examination, x-ray mammography, and sonography of the breast was carried out on 786 women having 77 excisional biopsies with 31 proven breast carcinomas. On breast sonography, 68% of the carcinomas were demonstrated with three false-positive diagnoses, compared with 65% cancer detection rate on physical examination with 37 false positives, and 77% detection rate on mammography with 15 false positives. Sonography was considered complementary to the other methods and of distinct usefulness after mammography (1) to examine the dense breast; (2) to study dense, poorly demonstrated areas; (3) to differentiate cystic from solid masses; and (4) to study breasts with augmentation mammoplasties. There were no added benefits in mammographically normal fatty breasts. The procedure was readily accepted by both women and their referring physicians.

Adult↗
PubMed1984

Automated water-path full-breast sonography: correlation with histology of 176 solid lesions.

A comparative study with mammography and physical examination showed that automated water-path whole-breast sonography contributed to the care of at least one-half of 786 study patients (separate report). Clinical application then followed in an additional 2530 women in whom there were 107 biopsy-proven cancers, 69 discrete biopsied benign lesions, and 121 biopsies of poorly defined lesions, usually some form of fibrocystic disease without a discrete mass. Breast sonography demonstrated 72% of the cancers and detected six cancers not seen on mammography. Although there was considerable overlapping of sonographic characteristics of benign and malignant diseases, most lesions were differentiated. Only 10% of the solid benign lesions had some characteristic of malignancy, and in 90% of the infiltrating duct carcinomas, findings suggested the histologic diagnosis. While breast sonography must be considered a complement to physical examination and mammography, the procedure can reliably differentiate the histologic types of at least 83% of discrete benign lesions and 75% of cancers. In 90% of all solid breast lesions, sonography differentiated benign and malignant processes.

Adult↗
PubMed1977

High risk breast tumor patients.

A unique scheme for placing the most breast carcinoma patients into the least population includes newly developed systems to analyse 64 clinical and radiographic risk factors in combinations. The calibration sample consisted of 540 cancerous and 641 non-cancerous breasts. In an independent validation sample of 73 carcinoma and 462 non-carcinoma breasts, 90 percent of the potential malignant breasts were correctly classified with only 12 percent of the non-malignant breasts misclassified. Thus, the scope of prediction and delineation of malignant and non-malignant and non-malignant groups is extended.

Breast Neoplasms↗