K Lerud | PubMed Health

PubMed1987

Methanol intoxication in multiple trauma.

Management of inflicted or self-inflicted trauma to accomplish homicide or suicide is no novelty in the practice of medicine. However, it takes an astute clinician to recognize serious poisoning in the midst of life-threatening injuries. We describe two cases where homicide and suicide attempts were accompanied with the ingestion of methanol. Both patients recovered with proper management of the injuries as well as early recognition and treatment of the methanol poisoning.

Adult↗

PubMed1983

Hydrocortisone reduces auditory sensitivity at high tonal frequencies in adult males.

The present study was designed to investigate the effects of treatment with cortisol on auditory tonal detection. College males were given either 20 mg of hydrocortisone or a placebo (dextrose) in a double blind design. Thereafter, thresholds were determined for frequencies of 500, 1,000 and 4,000 Hz using the method of limits. These results were then converted to change scores by using thresholds obtained for the same subjects at the same frequencies prior to treatment. Planned comparisons indicated that treatment with cortisol reduced sensitivity at 4,000 Hz but had no effects at other frequencies. Also, an overall analysis of variance indicated greater right ear improvement and greater improvement at lower frequencies. These findings are explained as resulting from the ability of glucocorticoids to alter cellular metabolism or reduce levels of adrenocorticotropic hormone.

Adolescent↗