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Biomedical subjects

K Levitsky

Publications and source records attributed to K Levitsky.

7 recordsLinked to original sources
PubMed1996

Osteoid osteoma of the calcaneus: an unusual cause of hindfoot pain in an adolescent athlete.

Osteoid osteomas are distinctive, benign tumors of bone that cause localized pain. This problem, although rare in athletes, must be resolved before pain-free competition can resume. We present a case of a 14-year-old white, male football player who complained of heel pain. He was treated conservatively with ice, stretching, and a nonsteroidal anti-inflammatory drug (Advil). Postseason, his symptoms worsened and he was referred for orthopedic consultation. Radiography displayed a possible osteoid osteoma; a CT evaluation confirmed the diagnosis. The athlete was treated surgically for the condition, and following a 2-week immobilization and a 3-week rehabilitation program, the pain completely resolved.

Journal Article↗
PubMed1992

Methods for assessing condition-specific and generic functional status outcomes after total knee replacement.

Many assume that, relative to generic measures, condition-specific health measures are both more sensitive to the condition's severity and more specific because they are less affected by other conditions. We analyzed the sensitivity and specificity of the generic SF-36, condition-specific scales based on the SF-36, and condition-specific measures based on the Knee Society's Clinical Rating System in a study of osteoarthritis patients following knee replacement. As hypothesized, knee-specific role function and pain measures were more specific than generic measures among patients with other comorbid conditions, and less so among patients with only knee problems. Physical function scales of both types were equally specific. Clinical indicators based on x-ray and range of motion were only weakly related to all measures of function.

Activities of Daily Living↗
PubMed1983

Immunoaffinity chromatography of a cellular tumor antigen from mouse neuroblastoma cells.

The cellular tumor antigen p53 was isolated from mouse neuroblastoma cells and was found in a form not complexed to another protein. The p53 in these cells was stable, turning over about every 10 h. Its methionine-labelled tryptic peptides were very similar to those of the p53 isolated from SV40-transformed mouse cells. The labelled protein was purified from neuroblastoma cells by immunoaffinity using specific monoclonal antibodies and was about 80% radiochemically pure. Furthermore, the purified p53 sedimented in sucrose gradients with a sedimentation coefficient of approximately 8S. This correlated with the sedimentation coefficient of p53 prior to purification, showing that the purified protein retained its native size.

Animals↗