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Biomedical subjects

K Luka

Publications and source records attributed to K Luka.

3 recordsLinked to original sources

[Histiocytosis X (Langerhans cell histiocytosis) of temporal bone. Role of scintigraphy in disease progress evaluation].

The authors present a case report of a 7-year-old girl with Langerhans cell histiocytosis of temporal bone. Edema and bone destruction involved zygomatic process of temporal bone and temporal fossa without ear occupation. The role of picturing diagnosis in evaluation of lesion extent with special importance of scintigraphy is discussed. Treatment methods of Langerhans cell histiocytosis lesions in temporal bone are presented. In our case locally Depo-Medrol injection was given and radiation was left as last resort management.

Child↗

Platelet function and survival in multiple myeloma.

Symptoms of haemorrhagic diathesis are frequently observed in multiple myeloma patients. Their nature is complex and is thought to be connected with platelet function disturbances, coagulation abnormalities and vascular endothelium damage. We demonstrated the shortening of platelet halflife in six myeloma patients. Disturbed thrombocytopoiesis, decreased platelet adhesion and aggregation were shown in all patients studied. The shortened platelet survival in our patients may have resulted from disturbed platelet function resulting from high immunoglobulin concentration and changes in thrombocytopoiesis.

Aged↗

A case of congenital factor XIII deficiency.

The case of a 53 years old woman was described in whom a congenital factor XIII deficiency was suspected because of deforming scars and hemorrhagic diathesis. A thromboelastographic declination of elasticity as well as decreased factor XIII level up to 5% of normal range were only found in all hemostatic examinations. In 2 children factor XIII decreased to half of its normal level, whereas in the youngest daughter that level was 25%. Sporadically the girl had mild diathesis. No changes in thromboelastograms were observed in members of the patient's family. The platelet function was unchanged in all examined cases.

Factor XIII Deficiency↗