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Biomedical subjects

K M McIntyre

Publications and source records attributed to K M McIntyre.

At least 55 records · Page 3Linked to original sources

Components of risk factor change in a CHD intervention program.

Carried out a study on a sample of men (N = 652) at high risk or coronary heart disease (CHD) in order to note the dimensions of change for the risk factors of smoking, blood pressure, cholesterol, selected intervention and psychosocial variables. The principal components analyses revealed a multi-dimensional structure with some bipolar change factors. Implications for the design and implementation of behaviorally oriented risk factor programs were discussed.

Adaptation, Psychological↗

The ratio of pulmonary arterial pressure to pulmonary vascular obstruction: index of preembolic cardiopulmonary status.

The magnitude of embolic obstruction by pulmonary angiographic studies has been shown to be directly related to the hemodynamic status after pulmonary embolism in patients free of prior cardiopulmonary disease; however, in patients with prior cardiopulmonary disease, the hemodynamic status after embolism may be determined either by the preembolic hemodynamic status, the magnitude of embolic obstruction, or both. No reliable index has been available to help determine the relative roles of embolism and preembolic hemodynamic disturbances in the postembolic hemodynamic status. The present study suggests that the ratio of the mean pulmonary arterial pressure to the pulmonary angiographic obstruction may effectively distinguish those patients in whom pulmonary embolism is the primary determinant of the postembolic hemodynamic abnormality from those in whom the preembolic hemodynamic abnormalities play the dominant role.

Adult↗

Echocardiographic evaluation of the Valsalva Maneuver in healthy subjects and patients with and without heart failure.

The Valsalva maneuver was evaluated by echocardiography in three groups: A) 10 normal volunteers, B) 10 patients with no history of heart failure and normal ejection fractions, and C) 10 patients with heart failure and depressed ejection fractions. Groups A and B had a significant fall in left ventricular internal dimensions and calculated stroke volume by end strain which returned rapidly to baseline in recovery without significant overshoot. Arterial pressure showed a signoidal strain pattern with a normal overshoot in early recovery in all group B patients. In group C ventricular dimensions did not diminish during strain; arterial pressures showed a "square wave" pressure elevation during strain without an overshoot in recovery. Echocardiography allows a new approach to evaluate further the left ventricular response to the Valsalva maneuver. Patients with severely depressed ejection fractions, unlike those with normal ventricular function, are unable to alter stroke output in response to acutely increased intrathoracic pressure. A square wave pressure response is a likely consequence of a fixed stroke output during the strain maneuver.

Adult↗