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Biomedical subjects

K Müller-Jensen

Publications and source records attributed to K Müller-Jensen.

At least 37 records · Page 2Linked to original sources
PubMed1993

[Surgical and conservative treatment of lagophthalmus (facial paralysis). II].

Thirty patients with irreversible facial palsy were treated with gold implants from 0.5 to 1.8 g. For the immediate treatment of postoperative facial palsies and reversible kinds of lagophthalmos, lead weights of 1.2 to 1.8 g ("lid dynamic eye dressing") are preferred to hourglass dressings. Insufficient orbicularis muscle function is compensated by the weight. The observation time for gold implants is more than 2 years; the fixation time of the adhesive lead weights is 1 to 10 days. Tolerance is excellent to both treatments. The principle is gravity dependent and is limited to the vertical and oblique head position. For sleeping at night, ointment application and pressure on the upper lid by a pillow are advisable; an additional hourglass dressing is possible. No serious keratopathies were seen in any cases. All patients found the return of lid motility from the restored levator muscle function to be a functional and cosmetic advantage. After weighing the advantages and disadvantages, especially the operative/technical expense in relation to the effective results, it would appear that simple lid-loading is so far the best method of treating lagophthalmos.

Adolescent↗
PubMed1992

[Gold implantation in lagophthalmos].

In 20 patients with irreversible facial palsy, dynamic voluntary lid closure was achieved by implantation of 0.8-1.6 g gold weights in the upper lid. Because of the high rate of efficiency, low complication rate and technical simplicity, this method is recommended more often than comparable procedures (magnet or wire-spring implantation).

Adult↗
PubMed1991

[The 32P-test in the diagnosis of intraocular melanoma--an obsolete study method?].

Results of the 32P uptake test for the diagnosis of choroidal melanoma in 41 patients are reported. The sensitivity was 80%, the specificity 86%, if a count rate ratio of more than 1.4 between tumor and normal tissue was considered as pathological. Ratios between 1.4 and 1.6 ought to be considered as equivocal in which case specificity increases to 90%. The 32P uptake test still remains a method of clinical relevance in the diagnosis of choroidal melanoma.

Choroid Neoplasms↗
PubMed1990

[Foudroyant course of AIDS-induced cytomegalovirus retinitis].

Of 57 patients at Karlsruhe Municipal Eye Hospital with manifest acquired immune deficiency syndrome, ocular involvement was found in 34%. In the prefinal stage (on average 6 months ante finem), 25% of these patients developed typical, rapidly progressing cytomegalovirus retinitis with intraretinal hemorrhages and necrosis, which responded well to combined intravenous and intravitreal DHPG therapy. Almost all the patients died of global respiratory insufficiency caused by pneumocystis carinii or atypical mycobacteria.

Acquired Immunodeficiency Syndrome↗
PubMed1981

[Anterior cleavage syndrome associated with endocrine orbitopathy (author's transl)].

A case of anterior cleavage syndrome in a 27-year-old female patient is described. It is remarkable for the unusual completeness and prominence of the symptoms. In addition to medodermal anomalies of the anterior segment (e.g., prominent ring of Schwalbe, posterior embryotoxon, peripheral anterior synechiae, hypoplasia of the iris stroma) the case also manifested microcornea, cataract, glaucoma, excessive myopia, partial anodontia vera with maxillary hypoplasia and telecanthus. It is the first time that Rieger's syndrome has been described in association with endocrine orbitopathy, caused by hyperthyroidism with isolated elevation of T3 in the blood serum and a soft struma. Possible genetic correlations and the role of the secondary glaucoma in the two syndromes are discussed.

Adult↗
PubMed1975

[Unusual courses of orbit-floor-fracture (author's transl)].

Blunt trauma can lead to intra-orbital haemorrhage, which cause motility and sensibility disturbances typically found also in orbit-floor fracture. When there is also a fracture present, it can be problematic to give the function deficiencies their right causes. Spontaneous improvement of the defiencies can be expected in a reasonable percentage of cases. Operative revision therefore should not be performed in cases of doubt, or in any case not earlier than 14 days after the injury. In a severe stove-in orbit with enophthalmos and double vision the operation should be preformed within the first week. In some cases, however, residual diplopia can be expected in spite of optimal early therapy.

Accidents, Home↗
PubMed1975

Membrane formation by autotransplanted retinal pigment epithelium (RPE).

Autotransplanted RPE cells after free intravitreal injection or in millipore diffusion chambers placed into the vitreous cavity undergo metaplasia: they first show the characteristics of macrophages. Later they transform into spindle-shaped cells or even into pigment epithelium-like cells. The latter two cell types have definite epithelial cell characteristics, such as cellunctions and basement membrane formation, clearly indicating that they are of ectodermal origin. These results support the hypothesis that RPE proliferation and metaplsia may play a major role in the formation of collagen-containing membranes, such as are found in massive periretinal proliferation (MPP).

Animals↗