PubMed Health⌕ Search

Biomedical subjects

K Marczewski

Publications and source records attributed to K Marczewski.

At least 19 recordsLinked to original sources
PubMed2001

[Some ethical and historical aspects concerning placental blood transfusion].

Recently, a greater interest is observed concerning the taking of placental blood in order to use it in future. This article pays attention to some ethical aspects like the ownership of the placenta or the possible commercial problems. We reminded the very first study on placental blood transfusion which took place before the World War II and also other abandoned methods used in transfusion in the past.

Blood Transfusion↗
PubMed2000

[About the beginnings of otolaryngology in Poland in commemoration of the 150th anniversary of Teodor Heryng's birthday and the 100th anniversary of the founding of the first Laryngology Ward in Warsaw].

In this study was remain biography of two pioneers of polish laryngology--Teodor Heryng and Leopold Lubliner. The first laryngological subdivision in Warsaw was localised in St. Roch hospital. The first full equipment laryngological division where was open in Jewish hospital.

History, 19th Century↗
PubMed1998

Does moxonidine increase cytotoxic activity of ethanol in rats? Preliminary report on the base of the ultrastructural study.

Combined effects of moxonidine and ethanol on ultrastructure of selected Wistar-Kyoto rat organs (kidney, liver, heart) were investigated. In cells of the animals, which received moxonidine alone, no morphological changes were found. In the group of rats which received alcohol, several typical submicroscopical changes were found, especially related to the mitochondria. After the combined administration of ethanol and moxonidine the pathological changes were bigger than those found in animals which received alcohol alone. Those changes were particularly significant in kidney and liver. The results might indicate that moxonidine increased cytotoxic activity of ethanol on several organs in rats.

Animals↗
PubMed1996

Day/night ratio of microproteinuria and blood pressure rhythm in type II diabetes.

The paper discusses the results of the studies conducted with a group of patients with type II diabetes without clinical nephropathy. The aim of the study was to attempt to determine the markers for early stages of diabetic nephropathy in NIDDM patients. The following examinations were carried out: the level of selected microproteinuric components, 24 h monitoring of arterial blood pressure, and electrocardiogram (ECG). Among the patients examined, the level of alfa-1-microglobulin, albumin and immunoglobulin G (IgG) in diabetic patients was higher than in the control group, and the increased activity of beta NAG was observed. The 24 h profile of blood pressure and the ratio afternoon/night of albumin excretion flattened in the majority of diabetic patients. The results of the study suggest that the proximal tubules and the membranes of renal glomeruli are damaged as early as during the period of subclinical diabetic nephropathy.

Adult↗
PubMed1996

[Microproteinuria and circadian rhythm of blood pressure in patients with arterial hypertension].

Microproteinuria is a recognized sign of early nephropathy in the course of arterial hypertension. There is few data concerning the excretion of proteins other than albumin in this group of patients. The aim of the study was to examine circadian rhythm of alfa-l-microglobulin (AlMG), albumin (ALB), immunoglobulin G (IgG) excretion and N-acetyl-beta-glukosaminidase (beta NAG)-activity, then to compare the results with the results of 24 hour ambulatory monitoring of arterial blood pressure in patients with arterial hypertension. The study comprised 28 patients. The control group included 27 healthy volunteers. Albumin concentration was determined by Beckman ICS2 nephelometer, using Beckman and Dako reagents. Blood pressure and ECG were monitored by analysis with ABP-system (AMP-USA). In patients with arterial hypertension significantly higher levels of ALB, AlMG, IgG and increased beta NAG activity were observed in morning urine samples. Despite hypotensive treatment blood pressure values were slightly, though significantly higher than in the control group. Among patients in the study circadian BP rhythm was disturbed. The results obtained suggest that in this group of patients subclinical nephropathy develops involving renal glomeruli and proximal tubules--probably resulting from vascular and humoral disorders, with accompanied hypertension.

Acetylglucosaminidase↗
PubMed1996

[Evaluation of the accuracy of arterial pressure measurements with different types of devices used for self-monitoring].

The self-control is the important item in hypertension treatment. The results of blood pressure measurements were received by using various types using different of oscillometric equipment (thumb, wrist and arm manket) and compared with the outcomes of mercury sphygmomanometer which was used in the same trial. The satisfactory correlation of results from different types of equipment was confirmed with the exception of the thumb oscillometric apparatus results.

Adolescent↗
PubMed1995

[The effect of human recombinant erythropoietin on levels of plasma phospholipids in patients chronically treated with hemodialysis].

In uremic patients a disturbed lipid metabolism is observed. In our former works a positive effect of erythropoietin (EPO) on blood platelet phospholipids composition in uremic patients was indicated. In this study we examined the EPO influence on blood plasma phospholipids in chronically hemodialyzed patients. Phospholipids were measured by thin layer chromatography method before and 3 months after the beginning of EPO treatment. EPO was administered subcutaneously, 2000 U twice a week. Decreased phosphatidylethanolamine, phosphatidylinositol and phosphatidylcholine levels were shown in patients before EPO treatment, compares with the control group. During EPO therapy the phospholipid levels approached to normal values. Conclusion is that EPO administration has a positive influence on blood plasma phospholipids in hemodialyzed patients. The detailed importance of this event has been not known yet, but our observations suggest that EPO profoundly interferes with lipid metabolism.

Adult↗
PubMed1994

[Change of platelet function after the beginning of repeated hemodialysis treatment in patients with uremia].

The disturbances of platelet function in end-stage renal failure varies in dialysed and non-dialysed patients. We examined some platelet function in 11 uremic patients treated conservatively (TC) and, again in the same patients, 3-month after the beginning of repeated hemodialysis treatment (HD). The blood samples were taken before hemodialysis. In TC patients normal platelet count, prolonged bleeding time, normal platelet aggregation, unchanged PF4 activity and decreased PF3 availability were shown, compared with control group. In HD patients also normal platelet count and prolonged bleeding time were noted, but increased platelet aggregation, increased PF4 activity and PF3 availability were observed, compared with control group and with TC patients. We conclude that in TC patients rather decreased platelet function was observed; after the beginning of hemodialysis treatment some platelet function became significantly enhanced, which suggests platelet activation. Moreover, in HD patients the disturbances of platelet function before dialysis were shown, then it is possible that platelet activation persists in interdialytic period.

Adult↗
PubMed1994

[Distribution of platelet membrane phospholipids in patients chronically hemodialyzed using cuprophane and cellulose acetate membranes].

The hemodialysis treatment is associated with a number of untoward events due to the blood-membrane contact. The severity of these reactions depends greatly on the kind of membrane. One of such effects is platelet activation with platelet membrane phospholipid translocation. The aim of this study was to assess the platelet membrane phospholipids distribution during hemodialysis through cuprophane (group I--12 patients) and cellulose acetate (group II--13 patients) membranes. Samples were taken before hemodialysis 14 days after treatment with the same dialyzer type. Phospholipids distribution was determined using a non penetrating tracer (TNBS) and by highly purified phospholipases hydrolysis. In patients of the group I a significant increase of phosphatidylserine and phosphatidylethanolamine at the outer platelet membrane surface was noted, as well as decrease in the other phospholipid classes, compared with control group. In patients of the group II the disturbances of phospholipid distribution were markedly smaller, and concerned only phosphatidylserine and sphingomyelin. Our data indicate that in patients dialyzed with the use of cuprophane membrane the disturbances of platelet membrane phospholipid distribution persist during the dialysis period. The milder intensity of these disturbances in patients treated using cellulose acetate suggests a better biocompatibility of this membrane.

Adult↗
PubMed1993

[Not Available].

Explore the source record for details and available documents.

Diagnosis↗
PubMed1993

The effect of pilocarpine on electrodermal resistance in chronic hemodialyzed patients.

Electric resistance of forearm skin was examined in 40 hemodialyzed (HD) patients under resting conditions and after subjecting the skin to the action of a 10% pilocarpine gel. The results were compared with a control group of a 100 healthy volunteers. An increased skin resistance was observed before dialysis and then a significant post-dialysis fall to the normal level followed. The response to the applied pharmacological stimulus in the HD group was similar to that in the control group. The results suggest that the rise in skin resistance in patients with renal failure and the so-called uremic dry skin, are not connected with the dysfunction of the glands themselves but rather with their insufficient stimulation.

Adult↗
PubMed1992

[Not Available].

Explore the source record for details and available documents.

Germany↗