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Biomedical subjects

K Martinsson

Publications and source records attributed to K Martinsson.

40 records · Page 3Linked to original sources

Thin sow syndrome (TSS): the effect of amperozide.

Sixty sows suffering from typical post-weaning TSS were divided into three groups: (1) 20 as negative controls (NC); (2) 20 as positive controls (PC) treated with vitamins, trace elements and antibiotics; and (3) 20 injected with amperozide (2 mg/kg body weight), a new neuroleptic compound with antistress and anxiolytic properties. Amperozide treated sows fully recovered (P less than 0.05) and 80% became pregnant, while figures for the PC and NC groups were only 15% and 10% respectively. Mortality was up to 50% in the NC, 40% in the PC and only 15% in the amperozide treated group (P less than 0.05). These field results warrant further studies in unravelling the aetiology and prevention of this condition.

Animals↗

The effect of pre-farrowing treatment of the sow with ivermectin on the early establishment of Ascaris suum and Oesophagostomum spp in the progeny.

Residual infective Ascaris suum eggs in farrowing pens provide the initial source of infection for piglets under Swedish management conditions. In such circumstances there is little evidence to support pre-farrowing treatment of the sow specifically against A. suum. The present study shows, however, that ivermectin-treatment of the sow prevents the early establishment of A. suum and Oesophagostomum spp in her litter.

Animals↗

The effect of continuous in-feed medication with thiophanate on Ascaris suum and Oesophagostomum spp. egg output in young pigs.

The full potential of anthelmintics now available for single dose treatment is not achieved because the devising system for worm control in piglets/weaners is not efficiently applicable in practice. Therefore an in-feed medication programme for growing young pigs, allowing only one feed lot to be handled by the farmer, was tested in two studies. Study A Feed containing 0.0225% thiophanate was continuously fed almost ad lib. to piglets from birth right up to about 25 kg body weight when ready for fattening. This control measure effectively prevented A. suum and Oesophagostomum from becoming established during the whole pre-fattening period, thus allowing "worm-free" weaners to be produced. -33% of animals receiving unmedicated feed harboured mature Oesophagostomum already at an age of 63 days when first examined. Three out of 97 unmedicated pigs were then A. suum egg-count positive. At the same time all medicated pigs, except one with a low Oesophagostomum egg output, were egg-count negative. All medicated were still egg-count negative at 23-29 days after the withdrawal of the feed. About 30% of unmedicated pigs were then shedding eggs of A. suum and Oesophagostomum respectively. At 45-49 days after the withdrawal of the medicated feed 8% of previously medicated pigs and 43% of unmedicated pigs were A. suum egg-count positive. The corresponding figures for Oesophagostomum egg-count positive pigs were 6% and 40% respectively. The acquisition of worm infections by previously medicated pigs most probably was made in the fattening unit after the withdrawal of the thiophanate medicated feed. Study B In this study it was further substantiated that in-feed medication of pigs with thiophanate prevents A. suum from becoming established. All treated pigs were A. suum egg-count negative at Day 43 and 46 after the withdrawal of the medicated feed whereas about 62% of untreated control pigs were shedding A. suum eggs at the same time. This finding justify the proposal that the in-feed medication performed prevented larval migration. Furthermore it was shown that the in-feed medication must proceed right up to the transfer of piglets to the fattening unit in order to achieve its full potential. Farrowing pens may be heavily contaminated with infective Oesophagostomum larvae at the end of the pre-fattening period resulting in sudden and heavy nodular worm infections after the withdrawal of the medicated feed.

Animal Feed↗

Epidemiology of porcine neonatal steatorrhoea in Sweden. 1. Prevalence and clinical significance of coccidal and rotaviral infections.

A study of neonatal steatorrhoea in unweaned piglets was carried out in randomly visited herds. Isospora suis and rotavirus were shown to be incriminated in this type of enteric disease and these agents may be considered important enteropathogens for 1-3-week-old piglets in Sweden. More extensive studies of I. suis were undertaken in one large herd. It was found that steatorrhoea may appear in 4-day-old piglets but oocysts were not detected until some days latter. Piglets that were shedding I. suis were not necessarily steatorrhoeic but oocysts were more frequently found in steatorrhoeic faeces than in faeces of normal consistency. The earliest oocyst output was detected at 5 days of age, the average litterage at first appearance being 12.8 +/- 4.0 days. The occurrence of I. suis oocysts in piglets did not correlate with the oocyst output in sows, which almost exclusively included genus Eimeria. Repeated parasitological and virological examination of steatorrhoeic faecal samples from 5-10 litters per herd at an age of 1-3 weeks would be helpful for making a herd diagnosis.

Animals↗