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Biomedical subjects

K Mayr

Publications and source records attributed to K Mayr.

16 recordsLinked to original sources
PubMed1990

Estimate of the dose due to 90Sr to the Austrian population after the Chernobyl accident.

In order to estimate the contribution of 90Sr to the exposure of the Austrian population, the ratio of 90Sr to 137Cs in 126 food samples and nine drinking water samples was determined. From this and the average activity concentration of 137Cs in each type of food as obtained by the measurement of some 100,000 food samples after the Chernobyl accident, a good estimate of the average activity concentration of 90Sr in these food items could be obtained. Samples were investigated at various times after the accident to take into account possible changes with time in the 90Sr-activity concentration and its ratio to 137Cs. Also, pre-Chernobyl samples were measured to estimate the relative contribution of the reactor accident and the fallout of the atomic bomb testing to the intake of 90Sr. Assuming average food consumption, the intake of 90Sr for an adult person amounted to 168 Bq in the first year and 115 Bq in the second year after the accident, resulting in an effective dose equivalent of 5.9 muSv and 4.0 muSv, respectively. This is a minor fraction of the dose due to the ingestion of Cs isotopes, which amounted to 360 muSv in the first year and 97 muSv in the second year. For the one-year-old infant, a 90Sr intake of 96 Bq (10.5 muSv) in the first year and 65 Bq (7.1 muSv) in the second year is estimated. Approximately 50% of the intake in the first year and 70% of that in the second year are due to 90Sr from nuclear weapons testing.

Accidents↗
PubMed1988

[Behavior of angiotensin converting enzyme in diseases of the thyroid].

Serum ACE activity was examined in cases of diseases of the thyroid gland. The enzyme activity was compared with the concentration of total serum thyroxine (TT4) and total serum triiodothyronine (TT3). For this purpose the medical data of a group of healthy test persons (85 male and 85 female) were contrasted with those of a group of 162 patients attending the out-patient department for thyroid gland diseases in our hospital (28 male and 134 female, of whom 112 were aged between 21 and 60, and 50 above the age of 60). Among the patients there were 36 cases of euthyroid goiter, 59 of untreated and 36 of treated hyperthyroidism, 25 of hypothyroidism of varied genesis, and 6 patients suffering from as yet untreated thyroid cancer. We observed significant differences in ACE activity in the different groups. In cases of disorder of the thyroid gland there was a positive correlation between enzyme activity and hormone data. Where other causes which may influence its activity can be excluded, ACE reflects the effect of the hormones of the thyroid gland on the tissue. We kept under observation 15 patients suffering from thyroid cancer altogether, of whom 6 had no previous treatment, whereas in 9 thyroidectomy had been carried out, followed by radioactive iodine therapy. Irrespective of the timing of the examination, there was a significant increase in serum ACE activity (on average 365 U/l, as against 282 U/l, p less than 0.01), if metastasis had occurred.

Adult↗
PubMed1985

[Angiotensin converting enzyme in lung diseases].

The aim of the study was to test the validity of ACE-determination for the differential diagnosis of pulmonary diseases. First details of the method, then the determination of the reference scale are discussed. The ACE-activity in the serum in 60 patients with sarcoidosis and 80 patients with other pulmonary diseases was measured. The sensitivity with which sarcoidosis can be established by means of the ACE-activity is to be examined. No positive correlation between the activity of the enzyme and the x-ray staging could be established, but active diseases requiring treatment could be distinguished from inactive forms to an unexpectedly high degree of reliance in our group of patients. The fact that in some cases of other pulmonary diseases--especially those connected with hepatopathy--higher ACE-activity is found as well, reduces the validity of the method. The determination of ACE comes up to all the criterias of a feasible, clinical-chemical method of analysis: practicability, reliance, high sensitivity and accuracy in a selected group, easy repetition. In some cases a typical x-ray result and corresponding clinical examination may provide the diagnosis of active sarcoidosis without further invasive methods of investigation; observation of the course of disease and adjustment of therapy are possible by means of the control of the ACE.

Alveolitis, Extrinsic Allergic↗
PubMed1975

[The significance of lipoprotein X in the diagnosis of obstructive jaundice: comparison with other biochemical tests (author's transl)].

The reliability of lipoprotein-X demonstration in the diagnosis of obstructive jaundice was tested in 660 patients (1105 samples) and compared with other biochemical studies. Groups of 100 patients each with morphologically proven liver or biliary-tract disease were analyzed in order to determine the frequency with which the demonstration of lipoprotein X and biliary stasis coincided. There was no direct connection between hepatitis B antigen and lipoprotein X. Total cholesterol concentration provided no help in the differential diagnosis of jaundice, although in a series of cases with and without obstruction the mean concentrations differed significantly. Intra- and extrahepatic causes of jaundice and their aetiology could not be clarified merely by demonstrating the presence or absence of lipoprotein X. Nonetheless, it is a simple and safe method for proving biliary stasis.

Alanine Transaminase↗