[Right-to-left shunt in the neonatal period: V. Determination of oxygen partial pressure in the blood using a metra-micro-measuring chamber].
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Biomedical subjects
Publications and source records attributed to K Menzel.
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162 immature and mature asphyctic newborns were treated by CPAP breathing. The overall survival was 42%. Taking babies without primary asphyxia not into account, 55% per cent survived. On children born before the 34. week of gestation, the therapeutic effectivity decreased markedly.
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Neuropediatric follow-up studies during 18 months of preterm born babies with birth weight below 1600 g show a normal development in 70%. Better perinatological and neuropediatric long-term care are taken as causes of the improved developmental prognosis of children at risk in recent years.
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The normal values of serum-CK-activity in healthy newborns varied greatly (95% range: 4--165 U/l; 257 probands) and the borderline to pathological values was not sharp. Brain-typical CK-isoenzyme (CK-BB) could be detected in serum of 6 of 8 infants with perinatal brain damage by means of agar gel electrophoresis. The combination of neuropathological symptoms, increased total-serum-CK-activity, and significant amount of CK-BB in serum seemed to be a sure sign of severe CNS-damage in newborns.