[HDL-cholesterol in patients with gout (author's transl)].
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Biomedical subjects
Publications and source records attributed to K Mikanagi.
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1. The age and sex distribution of the SUA of the Japanes people was the same as of the Caucasians. 2. The prevalence of gout was 0.4% of all the subjects, in adult male it was 1.2% and 76.4% in hyperuricemia above 10.0 mg/dl. 3. The incidence of a year throughout this population study was 0.02% per population. 4. Serum creatinine, body weight, height, age, urea-N, blood pressure and alcohol intake were strongly associated with SUA respectively. 5. Correlation analysis of SUA in familiar members showed the strong correlation between mother and son.
The clinical aspects of gout were described based on the 4,112 patients observed in the same clinic. In this paper mainly, 2,455 cases seen between 1958 and 1973 were described based on a pretrospective computer assisted analysis. The age distribution of the patient had its peak at 50 years of age and the average age at the time of onset was 49.5 years for males and 54.2 years for females. Recently, in Japan, the incident of gout among second and third decades has increased. The sex distribution, showed a predominance in males (99%). Primary gout in females before the neopause was very rare, only 0.08% of all subjects. Cases with a definite hereditary incidence comprised 7.5% and male sibling involvement was the most frequent. 68.4% of the patients had their initial gouty attack in the MTP joint of the great toe. 47.4% of the patients had a history of gouty attacks in two or more joints. Cases with tophaceous gout composed 9.2%, however, recently it has been decreasing in number every year.
Seven patients with severe lumbosacral spondylolisthesis were treated by reduction of the displacement followed by stabilisation by anterior interbody fusion. In the two youngest patients full reduction was achieved by halo-pelvic traction. In the remainder halo-pelvic or femoral traction was combined with a posterior wire reduction device. All patients achieved a sound fusion with complete remission of symptoms.
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