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Biomedical subjects

K Mikata

Publications and source records attributed to K Mikata.

32 records · Page 2Linked to original sources
PubMed1996

[Extirpation of total urinary tract as a final treatment for asynchronous multicentric urothelial cancer: a case report].

A 48-year-old male patient underwent transurethral resection (TUR) for solitary bladder tumor in January 1985. Pathological finding of the specimen was non-invasive transitional cell carcinoma (TCC) G2 > G1. Following the operation, prophylactic intravesical instillation of antitumor agents, intrapelvic irradiation, and hyperthermia were done for the recurrences. In June 1987, left renal pelvic tumor revealed, and nephroureterectomy was performed. Histological examination of renal pelvic tumor showed TCC G1. Five months later, multiple bladder tumors and right renal pelvic tumor were detected. A total cystectomy, partial nephrectomy and nephrostomy were performed in February and March 1988. Pathology of the bladder and right kidney were TCC G3. One month after these operations, tumors recurred in the rest of the right kidney. Complete remission was achieved after systemic chemotherapy with methotrexate, vinblastine, doxorubicin and cisplatin (M-VAC). In January 1992, right renal pelvic tumor recurred again. After two cycles of M-VAC therapy, the rest of the right kidney was extirpated. Postoperative hemodialysis has been uneventful. He has lived without tumor recurrence for three years after the introduction of hemodialysis.

Antineoplastic Combined Chemotherapy Protocols↗
PubMed1995

The phylogenetic relationships of Eeniella nana Smith, Batenburg-van der Vegte et Scheffers based on the partial sequences of 18S and 26S ribosomal RNAs (Candidaceae).

Two strains of Eeniella nana were examined for their partial base sequences of 18S and 26S rRNAs. In the partial base sequences of 18S rRNA (positions 1451 through 1618, 168 bases) the strains of E. nana have five, five, four and eleven base differences with those of Dekkera bruxellensis (type species), D. anomala (and Brettanomyces anomalus), D. naardenensis and D. custersiana, respectively. In the 26S rRNA partial base sequencings (positions 1611 through 1835, 225 bases and positions 493 through 622, 130 bases) the base differences were 46, 43, 34 and 40 and the percent similarities were 53-54, 51-54, 56-57 and 51-53, respectively. The sequence data obtained are discussed phylogenetically and taxonomically, especially on retention of the generic name Eeniella.

Base Sequence↗
PubMed1995

The phylogeny of Yamadazyma ohmeri (Etchells et Bell) Billon-Grand based on the partial sequences of 18S and 26S ribosomal RNAs: the proposal of Kodamaea gen. nov. (Saccharomycetaceae).

Two strains of Yamadazyma ohmeri were examined for their 18S and 26S rRNA partial base sequences. The two strains had identical or very similar partial base sequences to those of the type strain. All the three strains of Y. ohmeri were phylogenetically separated from any other accepted species of the genera Yamadazyma, Debaryomyces, Pichia, Williopsis, Metschnikowia, and Clavispora. Based on the sequence data obtained and the phenotypic characteristics, Kodamaea gen. nov. was proposed for the species.

Molecular Sequence Data↗
PubMed1995

The phylogenetic relationships of methanol-assimilating yeasts based on the partial sequences of 18S and 26S ribosomal RNAs: the proposal of Komagataella gen. nov. (Saccharomycetaceae).

Twelve strains of methanol-assimilating yeast species were examined for their partial base sequences of 18S and 26S rRNAs. In the partial base sequencings of 18S rRNA (positions 1451-1618, 168 bases), P. kodamae had the same partial base sequence as Ogataea minuta, and P. finlandica, P. pini, P. trehalophila, C. maris, and C. methanolovescens were the same in the partial base sequences as O. glucozyma. Candida boidinii and C. methylica were similar to O. glucozyma, but somewhat different from O. minuta (the base differences, one and four, respectively). Pichia naganishii had seven, four, six, and nine base differences with O. minuta, O. glucozyma, P. anomala, and P. membranaefaciens, respectively, and C. methanosorbosa did four, three, five, and twelve base differences. Pichia pastoris was quite different (the base differences among the methanol-assimilating yeasts, 32-31), and no bases were found in the fingerprint segment. In the partial base sequencings of 26S rRNA (positions 1611-1835, 225 bases; positions 493-622, 130 bases), P. finlandica, P. kodamae, P. pini, P. trehalophila, C. maris, C. methanolovescens, and C. methanosorbosa were similar to O. minuta and O. glucozyma. Pichia naganishii, C. boidinii, and C. methylica had somewhat different partial base sequences. The base differences and the percent similarities of P. pastoris were quite high (101-89) and quite low (40-47). Based on the sequence data obtained, the methanol-assimilating yeast species are discussed taxonomically and phylogenetically. A new genus, Komagataella was proposed for P. pastoris with a new combination, Komagataella pastoris.

Base Sequence↗
PubMed1995

The phylogenetic relationships of the Q9-equipped, hat-shaped ascospore-forming species of the genus Yamadazyma Billon-Grand (Saccharomycetaceae) based on the partial sequences of 18S and 26S ribosomal RNAs.

Sixteen strains of the sixteen species, including the type species, Y. philogaea (CBS 6696, type strain), of the genus Yamadazyma were examined for their partial base sequences of 18S and 26S rRNAs. The genus Yamadazyma Billon-Grand was found to have a heterogeneous nature phylogenetically. In the partial base sequences in positions 1451-1618 (168 bases) of 18S rRNA, the number of base differences was 4-0 within the genus except for Y. spartinae, Y. inositovora, Y. ohmeri, and Y. besseyi. The base differences numbered 6-1, 11-8, and 8-4 with D. hansenii, P. membranaefaciens, and S. cerevisiae, respectively. In the partial base sequences in positions 1611-1835 (225 bases) of 26S rRNA, the number of base differences was 14-0 within the genus. The base differences numbered 19-0, 31-24, and 25-17 with D. hansenii, P. membranaefaciens, and S. cerevisiae, respectively. In the partial base sequences in positions 493-622 (130 bases) of 26S rRNA, the percent similarities were 73-93. The percent similarities were 77-90, 64-71, and 68-79 with D. hansenii, P. membranaefaciens, and S. cerevisiae, respectively. Yamadazyma inositovora, Y. spartinae, and Y. ohmeri were not closely related phylogenetically. Yamadazyma besseyi (Q-7) was separate phylogenetically from the species mentioned above of the genera Yamadazyma, Debaryomyces, Pichia, and Saccharomyces (base differences, 13-7 and 62-17; percent similarities, 48-63). The discussion was made phylogenetically and taxonomically, especially on transferring Y. besseyi to a separate taxon.

Base Sequence↗
PubMed1995

The phylogenetic relationships of Pichia jadinii, formerly classified in the genus Hansenula, and related species based on the partial sequences of 18S and 26S ribosomal RNAs (Saccharomycetaceae).

We analyzed 18S and 26S rRNA partial base sequences [positions 1451-1618 (168 bases) of 18S rRNA and positions 1611-1835 (225 bases) and 493-622 (130 bases) of 26S rRNA] of a total of three strains of Pichia jadinii and Candida utilis. The three strains had identical base sequences with the type strain of P. jadinii (IFO 0987) in the 18S rRNA partial base sequencings. In the 26S rRNA partial base sequencings, there were partial base sequences similar to each other (1-0 base difference and 87-95 percent similarities). The sequence data obtained are discussed taxonomically and phylogenetically, especially in connection with Williopsis saturnus, the type species of the genus Williopsis Zender.

Base Sequence↗
PubMed1995

The phylogeny of Williopsis salicorniae Hinzelin, Kurtzman et Smith based on the partial sequences of 18S and 26S ribosomal RNAs (Saccharomycetaceae)

Williopsis salicorniae IFO 10733 (type strain), which is characterized by the formation of saturn-shaped ascospores, by the incapability of assimilating nitrate, and by a lower DNA base composition (36.7 mol% G + C), was examined for its partial base sequences of 18S and 26S rRNAs. In the 18S rRNA partial base sequencings, it had an identical base sequence with the type strain of Ogataea glucozyma (identical to Pichia glucozyma, identical to Hansenula glucozyma), which produces hat-shaped ascospores and has the ability to assimilate nitrate and methanol and a higher DNA base composition (45.1 mol% G + C). In the 26S rRNA partial base sequencings, the base differences were four, and the percent similarity was 87 between the type strains of the two species. The data obtained are discussed phylogenetically and taxonomically.

Base Sequence↗
PubMed1994

The phylogenetic relationships of the saturn-shaped ascospore-forming species of the genus Williopsis Zender and related genera based on the partial sequences of 18S and 26S ribosomal RNAs (Saccharomycetaceae): the proposal of Komagataea Gen. Nov.

The partial base sequences of 18S and 26S rRNAs of strains of Williopsis and Saturnospora species were analyzed. In the three regions partially sequenced, the higher base differences were observed in the strains examined of the three species, W. californica, W. mucosa, and W. pratensis, compared with those of W. saturnus var. saturnus (type species of genus Williopsis), W. beijerinckii, W. mrakii, W. saturnus var. subsufficiens, W. suaveolens, P. membranaefaciens (type species of genus Pichia), C. matritensis (type species of genus Citeromyces), and S'spora dispora (type species of genus Saturnospora): the percent similarities were 52-82 in positions 493-622, 130 bases, of 26S rRNA, and the number of base differences was 28-6 in positions 1611-1835, 225 bases, of 26S rRNA, and the number of base differences was 25-4 in positions 1451-1618, 168 bases, of 18S rRNA. In the 18S rRNA partial base sequencings, W. mucosa had an identical base sequence with P. anomala (identical to H. anomala, type species of genus Hansenula). Based on the sequence data obtained, the taxonomic positions of the three Williopsis species mentioned above are discussed. The genus Zygowilliopsis Kudriavzev was postulated to be retained and emended, and a new genus, Komagataea was proposed for W. pratensis with a new combination, Komagataea pratensis.

Base Sequence↗
PubMed1994

The phylogenetic relationships of the hat-shaped ascospore-forming, nitrate-assimilating Pichia species, formerly classified in the genus Hansenula Sydow et Sydow, based on the partial sequences of 18S and 26S ribosomal RNAs (Saccharomycetaceae): the proposals of three new genera, Ogataea, Kuraishia, and Nakazawaea.

The twenty-seven strains of the hat-shaped ascospore-forming, nitrate-assimilating species, formerly classified in the genus Hansenula, of the genus Pichia were examined for their 18S and 26S rRNA partial base sequencings. All the strains examined were separate phylogenetically from the type strain of P. membranaefaciens (type species of genus Pichia). Based on the sequence data obtained [by number of base differences (five or more) with P. anomala and base sequences on fingerprint segment] in the 18S rRNA partial base sequences, these species were divided into seven groups. Group I, including P. anomala (identical to H. anomala, type species of genus Hansenula), P. canadensis, P. muscicola, P. silvicola, P. subpelliculosa, P. americana, P. bimundalis, P. ciferrii, P. syndowiorum, P. bispora, and P. fabianii, corresponded to the genus Hansenula Sydow et Sydow. Groups II and III were comprised of P. capsulata and P. holstii, respectively. Group IV included P. angusta, P. minuta var. minuta, P. minuta var. nonfermentans, P. philodendra, P. glucozyma, and P. henricii. Groups V, VI, and VII included P. jadinii, P. petersonii, and P. dryadoides, respectively. The nitrate assimilation-negative species, P. wickerhamii was phylogenetically distant from P. membranaefaciens. The seven groupings are discussed phylogenetically and taxonomically. For Groups IV, II, and III, the three new genera were proposed as Ogataea, Kuraishia, and Nakazawaea, respectively, with the type species, O. minuta (identical to P. minuta), K. capsulata (identical to P. capsulata), and N. holstii (identical to P. holstii).

Base Sequence↗
PubMed1994

The phylogenetic relationships of species of the genus Dekkera van der Walt based on the partial sequences of 18S and 26S ribosomal RNAs (Saccharomycetaceae).

Eight strains of species of the teleomorphic genus Dekkera (and anamorphic genus Brettanomyces) were examined for their partial base sequences of 18S and 26S rRNAs. In the 26S rRNA partial base sequencings in positions 493-622 (130 bases) of 26S rRNA, D. bruxellensis (type species) (and B. bruxellensis, type species) and D. anomala (and B. anomalus) were related phylogenetically (percent similarities, 73-82). The percent similarity of D. naardenensis and D. custersiana were very low (48-56 and 48-53, respectively). In the 26S rRNA partial base sequencings in positions 1611-1835 (225 bases) of 26S rRNA, D. bruxellensis (and B. bruxellensis) and D. anomala (and B. anomalus) were related phylogenetically (base differences, 8-6). The base differences of D. naardenensis and D. custersiana were 46-38 and 38-27, respectively. In the 18S rRNA partial base sequencings in positions 1451-1618 (168 bases) of 18S rRNA, D. bruxellensis (and B. bruxellensis) and D. anomala (and B. anomalus) were closely related phylogenetically (base difference, one). The base differences of D. naardenensis were three with the above-mentioned two species. In contrast, D. custersiana was distant phylogenetically (base differences, 10-9). The sequence data obtained were discussed taxonomically, especially on setting up a new teleomorphic genus for D. custersiana.

Base Sequence↗
PubMed1994

The phylogenetic relationships of Rhodosporidium dacryoidum Fell, Hunter et Tallman based on the partial sequences of 18S and 26S ribosomal RNAs: the proposal of Sakaguchia gen. nov., a heterobasidiomycetous yeast genus.

The partial base sequences of 18S and 26S rRNAs of Rhodosporidium fluviale, R. lusitaniae, and Erythrobasidium hasegawianum were analyzed. In the 26S rRNA partial base sequencings, R. fluviale CBS 6568 and R. lusitaniae IGC 4599 and IGC 4641 had 81-82 and 77 percent similarities compared with R. toruloides (type species of genus Rhodosporidium) IFO 0559 and IFO 0880. Erythrobasidium hasegawianum IFO 1058 showed 69-71, 59, 63, and 61 percent similarities with R. toruloides IFO 0559 and IFO 0880, L. scottii (type species of genus Leucosporidium) IFO 1923, R. dacryoidum IFO 1930 and IFO 1931, and Kondoa malvinella IFO 1936, respectively. In the 18S rRNA partial base sequencings, R. fluviale CBS 6568 and R. lusitaniae IGC 4599 and IGC 4641 had zero and two base differences with R. toruloides. Erythrobasidium hasegawianum IFO 1058 showed ten, sixteen, three, and twenty base differences with R. toruloides IFO 0559 and IFO 0880, L. scottii IFO 1923, R. dacryoidum IFO 1930 and IFO 1931, and K. malvinella IFO 1936, respectively. Based on the sequence data obtained, a new genus, Sakaguchia was proposed for R. dacryoidum with a new combination, Sakaguchia dacryoides.

Base Sequence↗