Isolation and partial characterization of a polymorphic protein (Pm) in human parotid saliva.
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Biomedical subjects
Publications and source records attributed to K Minaguchi.
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In 218 parotid saliva samples collected at random from a Japanese population, two phenotypes were observed by SDS polyacrylamide gel electrophoresis. Inheritance was controlled by a dominant allele at an autosomal locus. The frequencies of the genes determining these phenotypes were for the Japanese population studied: Ph+ = 0.026 +/- 0.008, Ph- = 0.974 +/- 0.008.
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In 195 parotid saliva samples collected at random from a Japanese population, two phenotypes were observed by electrophoresis in acid-urea starch gels. The protein showing polymorphisms was detected in the middle zone between Pa and Pb, and was tentatively designated Pm. Inheritance was controlled by a dominant allele at an autosomal locus. The frequencies of the genes determining these phenotypes were, for the Japanese population studied, Pm+=.38+/-.03, Pm-=.62+/-.03.
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