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K Misumi

Publications and source records attributed to K Misumi.

70 records · Page 4Linked to original sources
PubMed1994

Principal component analysis, using the measurements during running and swimming test, in thoroughbred horses.

To investigate whether the running exercise fitness of individual horses could be assessed by a standardized swimming exercise test, the results of multivariate analysis of the exercise parameters measured during incremental running and swimming tests were compared. Ten thoroughbred horses were subjected to different types of exercise tests on a track or in a pool, and the maximum heart rate during and the blood lactate concentration immediately after the exercise were examined. Serial exercise parameters (VLA2, VLA4, LA0, V150, V200, HRS, HRLA2, HRLA4) referred to as the indices related to the adaptation of cardiovascular or metabolic systems were computed using the relationships between these measurements and velocity during each test, and were analyzed by a multivariate procedure, i.e. the principal component analysis. The correlation diagram between the exercise parameters on the first two component axes in running were similar to that in swimming. When the exercise fitness in each horse was compared between running and swimming, three horses trained by short-term endurance exercise were statistically distinguished in both tests and differed as a group from the other horses. Therefore, it is thought that evaluation of the exercise fitness in swimming using the multivariate analysis is useful for predicting poor performing horses on a track.

Animals↗
PubMed1994

The validity of swimming training for two-year-old thoroughbreds.

To investigate the validity of swimming training, the following matters were considered: 1) changes in the performance capacity, 2) changes in the constitution and 3) frequency of locomotor diseases. These were evaluated during a training program including both conventional exercise on a track and swimming. In this study, 24 two-year-old thoroughbred horses were studied, and divided into the following three groups: Group A, trained by only running; Group B, trained by running plus a gradual increase in swimming; Group C, trained by running plus constant swimming. As a result of standardized exercise tests, only the intercepts of the 3 regression curves between the speed and the blood lactate concentration in Group B increased significantly as the training progressed. While the growth in height in Groups B and C were greater than in Group A, the increase in girth and weight in Groups B and C were smaller than in Group A. The percentages with locomotor diseases during this experiment in Groups A, B, and C were 62.5%, 12.5% and 25.0%, respectively, and there was a significant difference (p < 0.05) between Group A and Group B. As mentioned, it was suggested that a training program including swimming training is seen as being useful for improvement in performance capacity, since it can reduce locomotor diseases in young horses and allow for smooth progress in future training.

Animals↗
PubMed1993

Left ventricular wall thickness in normal mongrel dogs.

To clarify the normal value of ventricular wall thickness we directly measured the ventricular wall thickness of 50 normal mongrel dogs of one year old. Because of a wide range in body weight from 6.0 to 16.0 kg of these 50 dogs, we selected 34 dogs weighing 8 to 12 kg to calculate the mean ventricular wall thickness as normal value of one year old. The results obtained were as follows; (1) The mean and standard deviation of the left ventricular wall thickness was 7.1 +/- 1.2 mm at anterior, 6.3 +/- 1.6 mm at posterior, 7.1 +/- 1.3 mm at lateral, 10.3 +/- 1.8 mm at the interventricular septum, and that of the right ventricular wall thickness was 3.4 +/- 1.0 mm. (2) Although any site of the ventricular wall thickness correlated significantly to heart weight, only the anterior left ventricular wall and interventricular septum barely correlated to body weight. (3) There was no significant correlation between arterial blood pressure and the ventricular wall thickness. Further study should be necessary to clarify influences of aging on the ventricular thickness and to determine the criteria of ventricular hypertrophy.

Alanine Transaminase↗
PubMed1993

Assessment of pulmonary edema based on extravascular thermal volume in dogs.

To establish criteria of pulmonary edema by extravascular thermal volume (ETV), ETV and a roentgenogram of the thorax were compared in normal and experimental hydrostatic pulmonary edema dogs. ETV was measured by the double indicator dilution technique using heat as a diffusible indicator and sodium ions as a non-diffusible indicator (thermal-Na method). Mean ETV in 14 dogs under physiologic conditions was 8.20 +/- 1.44 ml/kg. Comparison of ETV with the roentgenogram indicated the density of thoracic the roentgenogram to increase when ETV exceeded 11 ml/kg. Pulmonary edema was recognized clearly in the thoracic roentgenogram at more than 15 ml/kg of ETV. Further increase in ETV did not occur with additional radiographic change. ETV was significantly (P < 0.01) correlated with arterial oxygen tension (PaO2) but not statistically correlated with colloid oncotic pressure (COP), pulmonary arterial wedge pressure (PAWP) or PAWP-COP. Measurement of ETV would thus, appear to be a reliable method for evaluating the severity of pulmonary edema, which has been difficult to diagnose by roentgenography and should facilitate the early diagnosis and management of pulmonary edema.

Animals↗
PubMed1989

Endoscopic diagnosis of minute, small, and flat early gastric cancers.

We reviewed the diagnostic process in 6 minute, 6 small and 9 flat early cancers detected preoperatively, and in additional 12 flat cancers that were found in resected stomachs only at histology between 1976 and 1986. The limit of the size of cancer detectable preoperatively was 4 mm. Endoscopically, 7 out of 12 minute and small cancers detected preoperatively showed obvious morphological changes, while the others showed only color changes with or without erosion. Lesions with morphological changes significantly invaded the mucosa more often than those with no such changes (p = 0.010). Among flat cancers, color change was significantly more frequently observed in cancers involving the whole mucosa than in those confined to the superficial part of the mucosa (p = 0.015). Redness and discoloration were significantly more frequent in the differentiated and undifferentiated groups, respectively (p = 0.005). This study suggests that morphological and color changes are important indicators of minute or small cancers, especially those involving the whole mucosa.

Adult↗
PubMed1987

[A case report of successful immunochemotherapy of metastatic renal cell carcinoma using UFT and PSK].

The authors have monitored a case of renal cell carcinoma metastatic to the supraclavicular cavity over a twenty-year period following surgical removal of a cancerous kidney. The subject was a 67-year-old male who had his right kidney removed in 1963 because of renal cell carcinoma. In September of 1983, complaints of pain and an enlarged tumor in the left supraclavicular cavity during a physical examination led to a pathological diagnosis of clear cell carcinoma. Although chemotherapy using FT-207+ PSK was ineffective, there was a response to UFT+ PSK therapy which was deemed effective according to the criteria of Koyama and Saito. The findings suggested that UFT was effective in this case.

Aged↗
PubMed1978

Evaluation of fibergastroscopic biopsy in the diagnosis of gastric cancer: a study of 339 cases.

Three hundred and sixty-five biopsies under direct vision, using a fibergastroscope, were performed on 339 patients with gastric cancer from 1966 to 1975. Diagnostic accuracy improved with an increased in the number of biopsy specimens and reached 100% when 6 or more biopsy specimens were obtained. Positive specimens were obtained with 48.5% of the biopsied tissue from the center of the lesion (A), 52.2% from the inner margin of the lesion (B1), 19.6% from the outer margin of the lesion (B2), and 1.6% from the area around the lesion (C). The combined result of the biopsies from A and B1 was highly positive in 49 out of 51 cases (96.1%). Diagnostic accuracy of the early cancer reached 96.9%. This was significantly higher than that of advanced cancer (80.3%). False negative biopsies were found in 51 (16.3%) of the 313 patients who were gastrectomized and diagnosed by histological examinations. Twenty-three of the 27 patients, who were diagnosed as benign either by x-ray or endoscopic examination, and 4 of the 5 patients who were diagnosed as benign under both examinations, were found to have positive results by biopsy. Positive biopsy examination was particularly helpful with patients showing on inconclusive or benign diagnosis by x-ray and/or endoscopic examinations.

Biopsy↗
PubMedDate not supplied

Transabdominal operation for carcinoma of the gastric cardia: application of pulling-up retractor and EEA stapler.

In order to ascertain the advantages of the combined use of the pulling-up retractor and EEA stapler, we reviewed 88 patients who underwent surgery for upper stomach cancer between 1978 and 1986. The length of resected esophagus was significantly longer in patients operated on using an abdominal approach with this combination, as in those using a thoracoabdominal approach, than in those who were operated on using an abdominal approach with only the retractor or without the instruments (p less than 0.05). A relatively high incidence of leakage occurred at the anastomosis of the esophagus to the stomach or jejunum following operation using a transabdominal approach without the instruments. Pulmonary complication tended to be decreased in the non-thoracotomized patients compared to the thoracotomized patients. Postoperative radiogram following the combined use showed an esophagogastrostomy at a high level in the mediastinum. Our combination technique enables lymphadenectomy in the lower mediastinum and a sufficiently long enough resection of the esophagus without fatal complications.

Anastomosis, Surgical↗