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Biomedical subjects

K Mohan

Publications and source records attributed to K Mohan.

At least 73 records · Page 4Linked to original sources

Common childhood bacterial infections.

Acute bacterial infections are a common cause of pediatric visits to the emergency department. The diagnosis and treatment of pharyngitis, otitis media, pneumonia, urinary tract infection, acute bacterial lymphadenitis and gastroenteritis are reviewed. The authors propose the use of a limited number of antibiotic agents including penicillin, ampicillin, erythromycin, lincomycin, cephalexin, a sulfonamide and tetracycline to improve efficiency and quality of care and to allow physicians to become familar with the drugs' characteristics, indications, dosage and side effects.

Anti-Bacterial Agents

Comparative in vitro studies of cinoxacin, nalidixic acid, and oxolinic acid.

Cinoxacin and nalidixic acid were found to be similar in in vitro activity against 138 Shigella isolates and somewhat less active than oxolinic acid on a weight basis. Cross-resistance developed when 10 shigellae were transferred on increasing amounts of the respective agent contained in Mueller-Hinton agar. Plate dilution studies of the effect of changes in agar pH on the minimum inhibitory concentration revealed that the antibacterial activity increased with decreasing pH. Protein binding investigations revealed a high degree of binding, with nalidixic acid > oxolinic acid > cinoxacin.

Culture Media

Fracture of the shaft of the femur in children.

Sixty-five cases of fracture of the femur shaft caused by trauma in children under age 12 were studied. All were treated by various conservative methods. Two patients later underwent open reduction and internal fixation. Children below 5 years of age were treated by Bryant's suspension traction method. Older children were treated by balanced skin traction. In a few cases where the position was not acceptable, the fracture was reduced under general anesthesia and fixed traction was applied. Patients were discharged with a hip spica when the fracture site was nontender (average three weeks). Undisplaced fractures were treated by a primary hip spica. Functional end results were good in 81.5%, fair in 15.4% and poor in 3.1%. Eight compound fractures in this series were treated conservatively.

Bandages

Pelvic fractures.

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