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Biomedical subjects

K Mohan

Publications and source records attributed to K Mohan.

100 records · Page 6Linked to original sources
PubMedDate not supplied

Visual acuities after levodopa administration in amblyopia.

PURPOSE: To investigate the effect of the augmentation of levodopa with part-time and full-time occlusion on visual acuity and to determine its late results in amblyopia. METHODS: Seventy-two patients with amblyopia were prospectively studied and randomly distributed into groups A, B, and C consisting of 24 patients each. Group A patients received levodopa alone, group B received levodopa and part-time (3 hours/day) occlusion, and group C received levodopa and full-time (during all waking hours) occlusion of the dominant eye. Levodopa 0.50 mg/kg body weight, with a 25% fixed dose combination of carbidopa, was administered orally three times a day for 7 weeks. Snellen visual acuity and its logMAR equivalent were recorded before treatment, at weeks 1, 3, 5, and 7 after starting treatment, and every 6 weeks for 1 year after the completion of treatment. RESULTS: Fifty-three (74%) of the 72 patients had an improvement in visual acuity after treatment. Forty-four of the 53 patients with improved visual acuities completed 1-year post-treatment follow-up. Twenty-three (52%) of the 44 patients had a regression in visual acuity. CONCLUSION: The augmentation of levodopa with part-time or full-time occlusion does not enhance the recovery of vision in amblyopia. Improved visual acuity after levodopa administration persists at least 1 year in almost half of patients after cessation of treatment. Addition of full-time occlusion to levodopa helps maintain improved visual acuity for a longer duration compared to levodopa alone or combined with part-time occlusion.

Administration, Oral↗
PubMedDate not supplied

Spontaneous extrusion of cysticercosis: report of three cases.

We report three cases of spontaneous extrusion of cysticercosis. In two cases, it got extruded from the orbit and in one case from the subconjunctival space. Extrusion of cysticercosis was associated with improvement in clinical signs and symptoms.

Adolescent↗
PubMedDate not supplied

Norries disease.

A 2-month-old male infant was found to have Norrie's disease. The clinical presentation and detailed histological features diagnostic of the disease are discussed. This is the first authentic, histologically proven case of Norrie's disease from India. The absence of hearing loss and mental retardation at the time of presentation at the early stage of infancy and the fact that the case was sporadic do not detract from the diagnosis. However the child at the age of one year developed hearing loss.

Blindness↗
PubMedDate not supplied

Atypical Pasteurella haemolytica type A from poultry.

Atypical strains of Pasteurella haemolytica that failed to ferment maltose were isolated from nodular necrosis in the liver and heart blood of domestic fowl (Gallus domestica). These strains did not typically behave like either of the two well-known biotypes of P. haemolytica. The strains utilized trehalose and produced hydrogen sulfide (H2S), thus behaving like P. haemolytica type T, and produced acid in xylose but not in salicin, thus behaving like P. haemolytica type A. Most of the properties of the strains, however, conformed closely to those of P. haemolytica type A. Detailed characteristics of the isolates are described and discussed.

Animals↗
PubMedDate not supplied

Aerobic bacterial flora from dead-in-shell chicken embryos from Nigeria.

Dead-in-shell chicken embryos from two commercial hatcheries in Anambra State of Nigeria were investigated for isolation of aerobic bacteria. For this purpose, 79 pooled samples containing 632 dead-in-shell chicken embryos were cultured. From these samples, 23 isolates of Escherichia coli and 25 isolates of Staphylococcus aureus were recorded. Other bacterial species isolated included Micrococcus sp. (fifteen isolates), Klebsiella sp. (thirteen isolates), Pseudomonas sp. (nine isolates), and Proteus sp. (seven isolates). Salmonella, Streptococcus, and Mycoplasma spp. could not be isolated. A high incidence of pathogenic strains of bacteria from dead-in-shell chicken embryos was observed. This suggests that the isolates may have contributed to the embryonic mortality and reduced hatchability recorded in the farms investigated.

Animals↗