PubMed Health⌕ Search

Biomedical subjects

K Murooka

Publications and source records attributed to K Murooka.

13 recordsLinked to original sources
PubMed2000

New cytotoxic agents, BE-54238A and B, produced by a streptomycete.

New cytotoxic substances, designated BE-54238A and B, were isolated from the culture broth of Streptomyces sp. A54238. The active principles were extracted from the mycelium by methanol and purified by Diaion HP-20 and Sephadex LH-20 column chromatographies. BE-54238A and B exhibited cytotoxic activity against murine and human tumor cell lines.

Animals↗
PubMed2000

New cytotoxic agents, BE-52440A and B, produced by a streptomycete.

New cytotoxic substances, designated BE-52440A and B, were isolated from the mycelium of Streptomyces sp. A52440. The active principles were extracted from the mycelium by methanol and purified by silica gel column chromatography. BE-52440A and B exhibited cytotoxic activity against murine and human tumor cell lines.

Animals↗
PubMed1997

BE-32030 A, B, C, D and E, new antitumor substances produced by Nocardia sp. A32030.

New antitumor substances, designated BE-32030A, B, C, D and E, were isolated from the culture broth of Nocardia sp. A32030. The active principles were extracted from the mycelium by methanol and purified by Sephadex LH-20 and reversed-phase column chromatographies and finally by reversed-phase HPLC. BE-32030A, B, C, D and E inhibited the growth of P388 murine leukemia, DLD-1 human colon cancer, PC-13 human lung cancer and MKN-45 human stomach cancer cell lines.

Animals↗