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Biomedical subjects

K Murthy

Publications and source records attributed to K Murthy.

26 records · Page 2Linked to original sources

Hypernatraemic dehydration in the Hail region of Saudi Arabia.

Infants presenting with hypernatraemic dehydration were studied prospectively in order to describe its incidence and the predisposing factors. Five hundred and twenty children with gastroenteritis were admitted to the Paediatric Unit of Hail General Hospital over a 1-year period from 1 June 1985 to 1 June 1986. Twenty-five children (4.8%) had hypernatraemia (Na+ greater than 150 mmol/l) and all 25 were under 1 year of age, 23 (92%) being under 6 months. Twenty (80%) came from families living in the villages and had a poor educational background. All the babies were bottle-fed. The majority of the mothers did not know how to prepare food hygienically and with the appropriate water/milk proportions. Most of the infants presented with high fever (+39 degrees C) and the majority were underweight for their age. Two babies died and one had evidence of neurological damage. This study indicates that the incidence of hypernatraemic dehydration is significant in this region and causes serious morbidity and mortality. It confirms the importance of breast-feeding and the need to educate the public in the proper preparation of bottle feeds when breast-feeding is not possible.

Causality↗

Effect of fluoride dentifrices on salivary fluoride levels in children.

Fluoride dentifrices are well accepted for their caries preventive effects. The fluoride concentration in the oral fluids after tooth brushing with fluoride dentifrices may have an important relationship to the caries reducing capacity. The present study was aimed to clinically evaluate the salivary fluoride retention of dentifrices containing low fluoride concentration in 50 children, aged 7-9 years before, during and after the use of fluoride toothpaste. Estimation of fluoride in saliva was done using a Orion microprocessor ion analyser with a fluoride specific ion electrode. The results of the present study suggest that there is considerable salivary fluoride retention after brushing with fluoride dentifrices. The retention of fluoride in the saliva at a higher level even with the low fluoride concentration, proves the similar cariostatic effect as of higher concentration.

Child↗