Gross cholestatic dysfunction in giant cell arteritis.
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Aged↗
Biomedical subjects
K N Achar
Publications and source records attributed to K N Achar.
Biliary ultrastructural changes in the liver in a case of giant cell arteritis.
A 55-yr-old Palestinian man was admitted with a 1-month history of bi-temporal headache, proximal weakness and myalgia in the lower limbs. Both temporal arteries were swollen and tortuous. There was a moderate degree of cholestatic hepatic dysfunction. Temporal artery biopsy showed typical features of giant cell arteritis. Light microscopic examination of the liver showed no significant abnormality while electron microscopic (EM) examination revealed ultrastructural damage to the bile canaliculi. The patient improved dramatically on steroid therapy with normalization of cholestatic dysfunction. EM examination of a repeat liver biopsy 8 months later showed complete reversal of the biliary ultrastructural damage. The pathogenesis of the biliary injury remains uncertain.
Bile Canaliculi↗
Brown-Séquard syndrome following diphtheria and tetanus vaccines.
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Adolescent↗
Community-acquired bacteraemic Acinetobacter pneumonia with survival.
A 65 year old man was admitted with segmental consolidation of the left upper lobe after having stayed in a hotel for 2 days. He deteriorated rapidly on conventional antibiotic therapy and required ventilatory support. Acinetobacter calcoaceticus var. anitratus was grown from the sputum and blood cultures, which was treated with a combination of anti-pseudomonal agent, aminoglycoside and cotrimoxazole. He made a slow but remarkable recovery from the pneumonia. Acinetobacter is a rare potentially fatal cause of community-acquired pneumonia.
Acinetobacter Infections↗
Efficacy of ketamine infusion in refractory asthma complicated by acute myocardial infarction.
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Asthma↗
Severe hypokalemic rhabdomyolysis due to ingestion of liquorice during Ramadan.
A 62-year-old man was admitted with severe hypokalemia following ingestion of a modest amount of liquorice during the Islamic holy month of Ramadan. Hypokalemia was associated with typical electrocardiographic changes, marked acid-base disturbance and complicated by rhabdomyolysis. All abnormalities improved with normalisation of serum potassium. The serum creatine kinase isoenzymes (CK-total and MB) returned to normal over a prolonged period. The potential danger of ingesting liquorice even in small amounts over short periods, and the role of concomitant diuretic therapy with the additional factor of fasting during Ramadan in precipitating hypokalemia during liquorice ingestion are discussed.
Carbonated Beverages↗
Takayasu's arteritis and ulcerative colitis.
This report describes a case of Takayasu's disease and ulcerative colitis occurring simultaneously in a 35-yr-old Sri Lankan woman. It is suggested that these two diseases may be immunologically related and the possible pathogenic mechanisms by which these two disorders may be associated are discussed.
Adult↗