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Biomedical subjects

K N Sinha

Publications and source records attributed to K N Sinha.

At least 19 recordsLinked to original sources

Incorporation of a flap-valve at cardia, with esophagocardiomyotomy, for achalasia of the esophagus.

A lateral esophagocardiomyotomy extending from the level of inferior pulmonary vein to 3 cm on to the fundus of stomach for achalasia of esophagus was combined with a flap-valve constructed at the gastroesophageal junction. A total of 69 consecutive patients of achalasia cardia were subjected to this procedure between 1980 and 1994. There was no mortality. In a follow-up of up to 14 years, 73.9% patients had excellent results and 26.1% had good results. Recurrence of dysphagia and hiatus hernia were not detected and clinical, radiological and endoscopic studies did not show evidence of any significant gastroesophageal reflux.

Adolescent↗

Evaluation of peritoneovenous shunt in refractory cirrhotic ascites in Indian patients.

Ten patients with tense and refractory cirrhotic ascites underwent a modified peritoneovenous shunt procedure. Nine patients responded with complete resolution of ascites, mean weight gain of 5 (range 0-8) Kg, and rise in serum albumin level of 0.6 g/dL. Six patients improved from Child's class B to A. The longest survival period was 2.3 years. The main constraint in a developing country is the high cost of the shunt.

Costs and Cost Analysis↗

Immunodiagnosis in clinical practice.

Although the definitive diagnosis of diseases caused by worms and protozoa depends upon the demonstration of adult parasite or its ovum in excreta, blood and tissue biopsies of the patient, immunological methods can be of help in the identification of associated immunological syndromes, pathogeneses of these infections in man and as a guide to therapy. However, the non-availability of pure antigens is a limiting factor in effective application of these tests. The present paper describes the immunological syndromes associated with these diseases as well as some of the in-use immunodiagnostic tests.

Animals↗