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Biomedical subjects

K Neville

Publications and source records attributed to K Neville.

12 recordsLinked to original sources
PubMed2001

Developing actionable dietary guidance messages: dietary fat as a case study.

Although consumers say they are concerned about nutrition and are aware that eating a healthful diet is important for good health, this knowledge does not always translate into healthful diet behaviors or motivate behavior change. In an effort to better understand consumer attitudes about nutrition and to explore alternatives for communicating dietary advice in language that is meaningful and motivates behavior change, the International Food Information Council (IFIC) conducted qualitative research with consumers (using focus groups) and registered dietitians (using telephone interviews) in 1998 and 1999. Results of the research are presented using dietary fat as a case study. Findings from the IFIC research were reported to the Dietary Guidelines Advisory Committee to assist the Committee in developing meaningful and action-oriented dietary advice related to dietary fat for inclusion in the 2000 Dietary Guidelines for Americans that would be motivating and easy for consumers to implement. The recommendation to moderate fat intake in the new dietary guideline, "Choose a diet that is low in saturated fat and cholesterol and moderate in total fat" is consistent with communication recommendations in the IFIC research. Further, the moderate fat message is empowering because it suggests an achievable dietary regimen and reduces guilt and worry about foods. It allows flexibility to enjoy desired foods and promotes using common sense when it comes to diet. Several issues emerged from the IFIC research that apply to general nutrition communications with consumers, whether it be through national nutrition recommendations or in one-on-one counseling situations: to be effective, messages to consumers about nutrition, and specifically dietary fat, must address sources of discomfort about dietary choices; they must engender a sense of empowerment; and they should motivate both by providing clear information that propels toward taking action and appeals to the need to make personal choices.

Adult↗
PubMed2001

Acute poststreptococcal glomerulonephritis: public health implications of recent clusters in New South Wales and epidemiology of hospital admissions.

Acute poststreptococcal glomerulonephritis (APSGN) is an inflammatory kidney condition that can complicate Group A streptococcal infections. Two clusters of APSGN occurred recently in New South Wales (NSW), Australia; one in a rural town in December 1999 and the other in a Sydney suburb in January 2000. We interviewed carers of the affected children but found no common exposures except three of the Sydney cases were cousins in frequent contact. To assess the probability of these clusters occurring, we analysed hospital admissions for acute glomerulonephritis, as a proxy for APSGN in younger patients. The incidence of acute glomerulonephritis in NSW during 1989/90-1997/8 in residents aged under 20 years was 2.2/100000/year (95% CI 2.0-2.5). Incidence was highest in children aged 5-9 years, boys and Aboriginal children. We found no evidence for other clusters during that period. The recent clusters highlight the continued potential for unexpected future outbreaks of APSGN.

Acute Disease↗
PubMed1998

The relationships among uncertainty, social support, and psychological distress in adolescents recently diagnosed with cancer.

Uncertainty in illness about diagnosis, symptoms, prognosis, treatments, and relationships with health professionals is a major psychosocial stressor for adolescents recently diagnosed with cancer. In this study, the theoretical linkages of the uncertainty in illness theory of perceived social support, uncertainty, and psychological distress were tested. Respondents consisted of 60 adolescents between the ages of 14 and 22 years who were recently diagnosed with cancer. Data were generated by three questionnaires and analyzed using Pearson product moment coefficients and multiple regressional analyses. Hypotheses tested were that among adolescents with cancer (1) there will be an inverse relationship between perceived social support and uncertainty; (2) there will be a positive relationship between uncertainty and psychological distress; (3) there will be an inverse relationship between perceived social support and psychological distress; and (4) there will be an inverse relationship between perceived social support and psychological distress when controlling for uncertainty. Findings were as follows: the first three hypotheses were supported; there was no relationship between perceived social support and psychological distress when controlling for uncertainty. An interaction effect of perceived social support and uncertainty explained 39% of the variance in psychological distress.

Adolescent↗
PubMed1996

Psychological distress in adolescents with cancer.

A exploratory descriptive study was conducted to investigate psychological distress among middle and late adolescents recently diagnosed with cancer. Respondents consisted of 40 males and 20 females who were diagnosed with a malignancy within the past 100 days and received outpatient treatment. No gender difference was noted among adolescents, and adolescents did not score significantly different on the Brief Symptom Inventory from a healthy adolescent population. Among the various disease groups, adolescents with leukemia experienced the greatest psychological distress.

Adaptation, Psychological↗
PubMed1994

The third epidemic--multidrug-resistant tuberculosis.

We recently observed a striking increase in multidrug-resistant tuberculosis (MDR-TB) among patients admitted to the Chest Service at Bellevue Hospital Center in New York. We reviewed the laboratory susceptibility test results of 4,681 tuberculosis (TB) cases over the past 20 years, Combined resistance to isoniazid and rifampin increased from 2.5 percent in 1971 to 16 percent in 1991 with higher rates noted for individual drugs. We reviewed the medical records of 100 patients with drug-resistant TB, finding that these individuals were predominantly less than 40 years of age, minority, male, jobless, undomiciled, with a high percentage of drug abuse and human immunodeficiency virus infection. We conclude that the epidemics of AIDS and TB are complicated by a third epidemic of MDR-TB. This third epidemic requires urgent attention to achieve more rapid diagnosis, to develop new therapeutic regimens, and to address the social and hospital environment ot care for these individuals.

Adult↗
PubMed1986

Anxiolytic-like action of melatonin on acquisition but not performance of DRL.

The behavioural effects of melatonin have been attributed to a general reduction in motor activity; interference with memory fixation; a decrease in emotionality; or an anxiolytic action. The present experiments compared the effects of melatonin with an anxiolytic benzodiazepine, chlordiazepoxide (Librium), on a schedule of differential reinforcement of low rates of response (DRL) increasing 'burst' responding and premature responding. No doses of melatonin tested (0.03-8.1 mg/kg, IP) affected performance of well-learned DRL. Both low (0.03 mg/kg) and high (1.0 mg/kg) doses of melatonin impaired acquisition of DRL in a similar manner to chlordiazepoxide (5.0 mg/kg) and to much the same extent. Chlordiazepoxide had its usual effects on both acquisition and performance of DRL. These results show that melatonin shares a subset of the effects of chlordiazepoxide. The nature of the effects favours an 'anxiolytic' hypothesis of melatonin action rather than the other hypotheses so far proposed.

Animals↗