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Biomedical subjects

K Nowicka

Publications and source records attributed to K Nowicka.

44 records · Page 3Linked to original sources
PubMedDate not supplied

[RSV infections in children including managed cases in premature babies].

The authors assessed RSV infection issues within the Department of Neonatology during the year 2000/2001. The epidemiology, pathology, pathogenesis and the clinical course were discussed. The treatment and prevention patterns have been also presented. There were 5 cases of RSV infection of premature neonates within the Department of Neonatology. One of the mothers was probably the source of infection. The course of infection was described as severe in two infants (diagnosed respiratory insufficiency) and moderate in two other cases (respiratory disorders improved with n-CPAP). The symptoms of disease have been mild only in one case. Prematurity, age between 2-6 months, lung, and heart pathology and immunodeficiency must be considered as negative prognostic factors. Development of vaccination against RSV infection seems to be crucial solution for preterm neonates.

Female↗
PubMedDate not supplied

[Sural nerve phospholipids in some genetically determined nervous system diseases].

Phospholipid fraction pattern was determined in sural nerve in cases of suspected storage diseases. The material was obtained by means fo biopsy from 22 patients. In some patients features of polyneuropathy were found. Normal values of phospholipids were determined in 22 dying patients who had to neurological diseases. The most frequently observed change concerning the biochemical composition of the sural nerve in this material was a fall in the total amount of phosphatidyl ethanolamine (cephalin) and appearance of lysolecithins which are normally absent. In attempted correlation of histological and biochemical findings in the sural nerve with clinical signs of polyneuropathy it was observed that biochemical changes were present in cases without clinical evidence of polyneuropathy. Biochemical as well as histological investigations of sural nerve may help in intravital diagnosis of diseases belonging to the group of thesauroses.

Adolescent↗
PubMedDate not supplied

[Patients with multiple sclerosis among the Lódź population. I. Verification of the diagnosis and clinical characteristics].

Home-treated patients with multiple sclerosis who 5-6 years earlier had sought medical advice in neurological health service institutions were examined. Their age was to 46 years; they came from the population of the City Lódź. Slightly over half of them (53%) were patients whose disease had begun at the age of 20-29 years. In 18% of cases the duration of the disease exceeded 14 years. In 60% of cases the disease had a remitting course, in 83% of them multifocal involvement of the nervous system was present. In nearly all cases (97%) pyramidal tract involvement was present, and in 59% the optic nerves were involved. Females prevailed in this group (75%); the proportion of patients aged 40-46 years was higher among the females. In males the onset of the disease before the age of 30 years was significantly more frequent, while in females the proportion of cases beginning at the age of 30-39 years was significantly greater. Among patients aged up to 40 years registered within one year by the neurologists as certain or suspected cases of multiple sclerosis (independently of the duration of the disease) about 7% patients died in a period of 5.7 years on average (10.5% males and 5.3% females). These observations suggest a different onset or course of the disease in both sexes in this population.

Adult↗
PubMedDate not supplied

[Patients with multiple sclerosis among the Lódź population. II. Clinical course of the disease and patient fitness].

The motor fitness was assessed in multiple sclerosis patients remaining in their homes in the City of Lódź. The age of the patients was up to 46 years; 5-6 years earlier they had been registered within one year in neurological health service institutions after variously long periods of the disease. The proportion of those with severe motor impairment was 14%, and it was highest (17%) in the groups with disease duration 10-14 years. Nearly half of the group, independently of the age, sex and disease duration, were patients who could move about and perform household works. The proportion of fully fit and nearly fully fit was highest (83%) among those whose disease began under the age of 20 years, and it was lowest (42%) in those with disease onset at the age of 20-29 years. A tendency was observed for a different development of motor function impairment in both sexes depending on the age, age at disease onset and disease duration. In the light of the obtained results it is estimated that in the population of cities in Poland in the whole group of multiple sclerosis patients or subjects with suspected multiple sclerosis registered within one year after variously long disease duration about 40-50% remain after 5-6 years still completely or nearly completely fit.

Activities of Daily Living↗