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Biomedical subjects

K P Smidt

Publications and source records attributed to K P Smidt.

7 recordsLinked to original sources

Radio-iodine treatment of hyperthyroid cats.

Thirty-two elderly domestic shorthaired cats (mean age 12.9 years) were treated with radioiodine (131I). The dose of 131I administered ranged from 39 mBq to 134 mBq. Twenty-eight cats became euthyroid after treatment, one became hypothyroid and three remained hyperthyroxaemic. Two of the hyperthyroxaemic cats were successfully re-treated with 131I. Five cats died from concurrent diseases within one year of treatment. The administration of a dose of 131I selected by assessing the severity of the clinical signs, the size of the thyroid gland(s) and the serum level of thyroxine was an effective treatment for hyperthyroidism.

Journal Article↗

Splenic scintigraphy: a large congenital fissure mimicking splenic hematoma.

This report describes a case of blunt abdominal trauma in which a deep congenital fissure in the superior border of the spleen led to the preoperative scintigraphic diagnosis of a splenic hematoma. The frequency of splenic notches of this magnitude is low but significant, hence anatomical variation should be considered in the differential diagnosis of scintigraphic defects.

Adolescent↗

Undetected latrogenic hypothyroidism: a late complication of radio-iodine therapy.

The thyroid status of 317 patients treated with radioactive iodine between 1951 and December 1971 was investigated. Information was obtained on 236 patients and hypothyroidism, either treated or untreated, was present in 48 percent of women and 37 percent of men at mean follow-up intervals of 5.5 and 4.4 years respectively. Ninety-four of the 241 patients still alive were assessed personally by clinical examination and serum thyroxine assay, and 10 were found to have previously undiagnosed hypothyroidism. Seven of these patients had symptoms and in five these symptonms were the cause of significant distress. The importance of undertaking a long term review programme following radioactive iodine therapy is emphasised.

Adenoma↗