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Biomedical subjects

K Pavithran

Publications and source records attributed to K Pavithran.

At least 55 records · Page 3Linked to original sources

Vitiligo following type II lepra reaction.

A middle-aged male with lepromatous leprosy developed bouts of skin lesions of depigmented macules and patches of vitiligo, just following attacks of type II lepra reaction each time. In view of the present concept of autoimmunity playing a role in the pathogenesis of vitiligo as well as lepra reaction, their association in our patient appears to be more than fortuious. The depigmented macules persisted even after regression of skin lesions of leprosy following chemotherapy. The vitiligo macules responded partially to topical and systemic psoralen therapy.

Autoimmune Diseases↗

Relapse of paucibacillary leprosy after short course multidrug therapy.

Among 25 patients who had short-course multidrug therapy as recommended by the WHO for paucibacillary leprosy, 3 were observed to develop relapse of their disease 8 to 12 months after completion of treatment. These three cases of relapse are reported in detail. The duration of chemotherapy recommended by the WHO in paucibacillary cases appears to be too short.

Adult↗

Chromoblastomycosis in a residual patch of leprosy.

A middle aged male who had adequate dapsone monotherapy for borderline tuberculoid leprosy developed chromoblastomycosis within the residual analgesic patch during the post-treatment follow up period. Cladosporium carrionii, the causative fungus was isolated from culture in Sabouraud's agar. There was prompt therapeutic response to oral ketoconazole. The possible factors for development of chromoblastomycosis in this patient are discussed.

Chromoblastomycosis↗