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Biomedical subjects

K Pecze

Publications and source records attributed to K Pecze.

At least 19 recordsLinked to original sources
PubMed1997

[T-cell large granular lymphocytic leukemia associated with pure red cell aplasia, successfully treated with cyclophosphamide].

Authors report effective treatment of T-cell large granular lymphocyte (LGL) leukaemia and secondary pure cell aplasia with cyclophosphamide. The current classification of LGL proliferations is presented, with emphasis on the issues of diagnosis, clinical course and treatment. LGL proliferations are not so rare that previously thought and should be involved in the differential diagnosis of neutropenia, pure red cell aplasia, Felty's syndrome and vasculitis of unknown origin.

Antineoplastic Agents, Alkylating↗
PubMed1991

[Successful cyclosporin therapy of acquired hemophilia caused by factor VIII (VIII:C) inhibiting antibody].

A 47-year-old woman is reported who had a life-threatening, subarachnoideal bleeding due to the spontaneous development of factor VIII:C inhibitor. Cyclosporin combined with prednisone allowed a full recovery and the elimination of antibody even when other therapeutic facilities failed to be effective. Actual problems of treatment of factor VIII inhibitors are briefly surveyed.

Antibodies↗
PubMed1990

[Primary lymphoma of the bladder].

The authors present the case of a 74-year-old man in whom bladder tumor was detected the reason for haematuria. The histological investigation of transurethral resected pattern showed lymphocytic lymphoma. In possession of the histological finding detailed haematological examination has been carried out, the patient was without evidence of lymphoma dissemination. He received multichemotherapy (6 courses) and locoregional cytostatic therapy and complete clinical remission was detected. The authors report our experience with extranodal bladder lymphoma included diagnostic and therapeutical notes as well as a review of the relevant literature.

Aged↗
PubMed1990

[A case of successfully treated cyclic amegakaryocytic thrombocytopenic purpura].

The case of a patient with cyclic, acquired, periodically amegakaryocytic thrombocytopenia is described. On the base of a seemingly typical megakaryocytic thrombocytopenia ITP was diagnosed at first. He did not respond to steroid, therefore splenectomy was performed. He relapsed and thereafter severe thrombocytopenia was observed, periodically, for 8-10 days in every five-six weeks. During the cytopenic periods recognizable megakaryocytes and precursors were totally absent from the bone marrow. After the haemorrhagic periods platelet counts elevated to normal or even higher levels and the marrow was plenty of megakaryocytes. Vincristine was unsuccessful, but cyclosporine administration for a longer time was not without success. The patient has a normal platelet count since one year. No similar case of cyclic amegakaryocytic thrombocytopenia was found in the literature.

Bone Marrow Examination↗
PubMed1990

Effect of tetracycline on lymphocyte antigen expression.

Nowadays the existence of bearing both T and B marker lymphocytes has generally been accepted, but their role and nature is still unknown. The effect of tetracycline on lymphocytes was examined in 26 patients with different, mainly respiratory infections. Examinations were carried out on lymphocyte populations with T and B cell count using E rosette and surface immunoglobulin as a marker. It has been shown that on the lymphocytes of patients receiving tetracycline, regularly high number of D cells are found.

Acne Vulgaris↗
PubMed1989

Cytochemical studies in the blastic transformation of chronic granulocytic leukaemia.

The cytochemical features of blast cells were studied in 45 patients with blastic phase of chronic granulocytic leukaemia. Various degrees of Sudan black B positivity was characteristic of myeloblastic transformation (23 patients), while in the medullary blast cells of nine patients with myelomonocytic transformation the alpha-naphthyl-acetate esterase showed intensive activity. In two cases the demonstrability of beta-thromboglobulin and factor VIII-related antigen in blast cells showing otherwise PAS, acid phosphatase and alpha-naphthyl-acetate esterase activity referred to megakaryocytic transformation. In six patients with lymphoid blast crisis proliferation of the Sudan negative blast cells with different granular PAS, acid phosphatase and/or beta-glucuronidase positivity was demonstrated. In five cases the cytochemical findings of leukaemic cells indicated biphenotypic and mixed transformation, respectively.

Blast Crisis↗