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K Pfadenhauer

Publications and source records attributed to K Pfadenhauer.

33 records · Page 2Linked to original sources

[Thoraco-abdominal manifestation of stage II Lyme neuroborreliosis].

In the past little attention was paid to the thoracoabdominal manifestation of Lyme radiculoneuritis, because paralysis of the abdominal wall muscles was considered to be a very uncommon clinical manifestation of Lyme neuroborreliosis. In a group of 90 patients suffering from early stage Lyme neuroborreliosis we found abdominal wall weakness in 11 cases. In the majority of patients thoracoabdominal radiculoneuritis was located in the lower thoracic segments (Th 7-12) and involved more than 3 segments (62%) mostly bilaterally (69%). Abdominal wall paralysis was mostly bilateral (91%) and involved always the lower half of the abdominal wall. It was very severe in 18%. Electromyographic studies were done in the paraspinal and abdominal wall muscles showing fibrillation potentials and positive sharp waves in 86% and 50%, respectively. Diagnosis of thoracoabdominal radiculoneuritis in Lyme neuroborreliosis may be difficult and diagnostic errors may occur. Therefore we recommend to look carefully for paralysis of the abdominal wall, which can easily be overlooked on routine neurological examination. In patients from an area with a high incidence of Lyme disease it is recommended to exclude neuroborreliosis even in patients with known diabetes mellitus in order to avoid the misdiagnosis of diabetic thoracoabdominal radiculopathy. This has occured in 2 of our patients.

Abdominal Muscles↗

Spinal manifestation of neurolisteriosis.

Spinal symptoms in acute bacterial meningitis are rare. In a series of 10 cases of neurolisteriosis, we observed 2 spinal complications, one due to an acute intramedullary abscess, the other caused by chronic spinal arachnoiditis. Therefore, if spinal symptoms develop in acute bacterial meningitis, Listeria monocytogenes infection should be considered and early adequate antibiotic treatment be implemented.

Abscess↗

[Color-coded duplex ultrasound of the vertebral artery: normal findings and pathologic findings in obstruction of the vertebral artery and remaining cerebral arteries].

AIM: The aim of this study was to determine normal values of flow velocities in the extracranial vertebral artery (VA) with regard to diameter of the VA, blood pressure and age. Hemodynamic changes in the VA in occlusive disease of the brain supplying arteries were also to be investigated. Based on the findings the clinical value of CCDS for the investigation of the VA were to be assessed. METHOD: The evaluation was carried out by a CCDS-scanner with a 7.5 MHz transducer in 85 normal individuals and in 166 patients with occlusive disease of the cerebral arteries. RESULTS: The average maximal systolic flow velocity was 59 +/- 17, time averaged maximal velocity 31 +/- 10 and enddiastolic velocity 19 +/- 8 cm/sec. Significantly reduced flow velocities were found in severely stenosed and in occluded VA increased flow velocities in VA serving as collateral pathway in higher grade obstructions of contralateral VA, ICA, and SCA. CONCLUSION: CCDS of the VA is a valuable tool in diagnosis of severe obstructions of the VA, but also for demonstration of collateral flow. Furthermore, cervical collateral pathways in severe obstruction of the VA-origin can be detected. Diagnosis of moderate stenosis of the ostium of the VA remains difficult.

Adolescent↗

[Adenomatous hypophyseal apoplexy. Clinical, diagnostic and therapeutic aspects of a frequently misdiagnosed emergency state].

Pituitary adenoma apoplexy was considered an acute life-threatening condition until more benign and even asymptomatic courses were found by advanced neuroimaging procedures. Necrosis and hemorrhage in the pituitary adenoma can cause acute enlargement of the tumor. sometimes with rupture of the tumor capsule and bleeding into the subarachnoid space and surrounding parts of the brain. Clinical symptoms include acute or subacute headache in combination with signs of meningeal irritation and neuroophthalmological and cerebral dysfunction. Severe panhypopituitarism may be an additional complication. Acute blindness due to compression of the optic chiasm and symptomatic compression of basal cerebral arteries require immediate transsphenoid tumor resection. If panhypopituitarism is suspected, immediate hormone substitution is necessary.

Adenoma↗

Prognosis of facial palsy in Borrelia burgdorferi meningopolyradiculoneuritis.

Out of 72 patients treated for Borrelia burgdorferi meningopolyradiculoneuritis facial palsies occurred in 22 (12 unilateral, 10 bilateral). Eleven of the 32 pareses were initially complete. By the follow-up examination patients had recovered well with slight sequelae in 22% without cosmetically disfiguring pareses or synkinesias. Electrophysiological studies revealed axonal damage of the nerve as the underlying mechanism.

Adult↗

[Acute cerebellar syndrome in preventive lithium treatment and atypical pneumonia in Q fever].

CNS-involvement in Coxiella burnetii infection is rare. Severe cerebellar symptoms with incomplete restitution were observed in 3 patients who developed Q-fever pneumonia associated with a long-term prophylaxis with lithium for manic-depressive disorder. Several pathophysiological mechanisms for these complications are discussed and a specific toxic-infectious interaction is suggested.

Acute Disease↗

Significance of transcranial Doppler CO2. Reactivity measurements for the diagnosis of hemodynamically relevant carotid obstructions.

Transcranial Doppler ultrasonography can be used to determine CO2 reactivity in the large basal cerebral arteries. CO2 reactivity is expressed as percentage increase of mean flow velocity above one volume percent of CO2, using a reference value of 40 mmHg pCO2 normalized autoregulatory reserve. A normalized autoregulatory value of 15 as the lower limit of the normal range clearly separates patients with internal carotid artery obstructions greater than or equal to 70% from the control group. Stenoses of the ipsilateral internal carotid artery of greater than or equal to 70% result in a significant decrease of normalized autoregulatory reserve in the middle cerebral artery, which can be normalized by removal of the upstream flow obstacle using a carotid thromboendarterectomy. The scatter of normalized autoregulatory values in severe internal carotid obstructions indicates the variability of collateral circulation A retrospective comparison of normalized autoregulatory reserve and ipsilateral ischemic symptoms in the supply area of the internal carotid artery reveals a significant correlation between clinical symptoms and reduced normalized autoregulatory reserve.

Adult↗

Bilateral occlusive carotid disease: simultaneous or staged operation?

In a series of 231 carotid operations in 202 patients, 8 patients were operated on bilaterally by staged (group A), and 15 patients by simultaneous procedures (group B). Additionally 4 patients had a combined external carotid desobliteration plus extra-intracranial arterial bypass (group C), 3 of them in a simultaneous operation. Patients of the groups A and C had an uneventful recovery throughout. An additional group A patient, however, died during the staging interval due to an ischemic cerebral infarction at the not-yet-operated side. In group B one patient died after myocardial reinfarction and 4 showed other complications: diffuse hematoma of the neck, temporary palsy of the hypoglossal nerve, temporary left brainstem deficit and respiratory failure. Nevertheless, it is concluded that simultaneous bilateral carotid reconstruction offers specific benefits i.e. no risky interval, no second anesthesia and a reduced hospitalization period, and can therefore be recommended in selected cases.

Aged↗

[The reliability of computer tomography in the diagnosis of recurrent symptoms after lumbar disc operations].

In 67 patients with recurrent complaints after operations of herniated lumbar disks, the CT findings were compared with the results of the subsequent second operation. Postoperative complications as haemorrhages or inflammations appear as localised or diffuse densities within the spinal canal in the operated segment and can be diagnosed without difficulty. The differentiation between a true recurrent herniation and scar formation is difficult, mainly within the first 4 weeks after operation. Even with the administration of iv. contrast medium, the diagnostic accuracy is not higher than 70%. In addition to the enhancement effect, which is not always reliable, the shape, position and density of a suspected structure can be used as diagnostic criteria.

Adult↗