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Biomedical subjects

K Pintar

Publications and source records attributed to K Pintar.

29 records · Page 2Linked to original sources
PubMed1976

Pathological changes in surgically removed aortocoronary vein grafts.

Pathological changes in aortocoronary vein grafts were investigated in 17 patients who had a second revascularization procedure 1 to 53 1/2 months after their initial operation. Subendothelial proliferation was present in all grafts and had resulted in total occlusion of 7. With increasing duration of implantation the proliferative lesions tended to show hyalinization and to affect the media. Advanced atherosclerosis had developed in 2 grafts.

Adult↗
PubMed1976

A diffuse form of pulmonary silicosis in foundry workers.

Pulmonary silicosis usually is characterized by typical hyalinized, concentric nodules as seen under the microscope and in the corresponding roentgenogram. In the case of three foundry workers, lung biopsy specimens contained no nodules. The chest roentgenograms were not suggestive of silicosis. Examination of the biopsy tissue by scanning electron microscopy and energy dispersive x-ray analysis (EDXA) revealed significant (P less than .05) amounts of silicon in the thickened fibrous tissues of septa, pleura, and around blood vessels, enough to permit the diagnosis of silicosis. All three patients had severe functional impairment. It is not clear at this time what factors were responsible for a diffuse distribution of silicon in these cases.

Humans↗
PubMed1975

Identification of foreign material in lung by energy dispersive x-ray analysis. A new approach to silicosis.

Conventional methods for the detection of foreign material in the lungs are not only difficult but make it impossible to study any relationship between the material and the surrounding tissue. The present study employs energy dispersive x-ray analysis and scanning electron microscopy as the basis of a rapid and accurate method for determining the amount of silicon in the lungs of normal subjects and subjects with silicosis. A statistical evaluation of the data suggests that a silicon/sulfur ratio below 0.2 may be considered normal, whereas, a ratio above 0.3 may be considered to indicate silicosis.

Clinical Trials as Topic↗
PubMedDate not supplied

Atherosclerosis in aortocoronary bypass grafts. Morphologic study and risk factor analysis 6 to 12 years after surgery.

Segments of aortocoronary vein grafts from a selective group of 42 patients who underwent a second revascularization procedure or came to autopsy 6 to 12 years after coronary bypass surgery were studied. Complex atheromata often associated with an acute thrombus were present in 71% of the grafts. In 14% of the cases, aneurysms of the atherosclerotic type were noted. The medical records of 40 of these patients were reviewed. Special attention was paid to risk factors associated with coronary artery disease. A control population of 535 patients who had undergone coronary artery bypass surgery and had not had recurrence of symptoms requiring reoperation 5 or more years later was drawn from the Milwaukee Cardiovascular Data Registry. Significantly higher triglyceride and cholesterol levels and lower high density lipoprotein levels were noted in the patients undergoing two bypass procedures. In addition more diabetics, cigarette smokers, and patients with abnormal lipoprotein phenotypes were noted in the study group. Hypertension did not appear to be a significant risk factor. Atherosclerosis appears to be an important factor in late graft failure. Vein grafts that develop atherosclerosis appear to be susceptible to aneurysm formation. Risk factors associated with atherosclerosis in coronary arteries also appear to play a role in the development of atherosclerosis in aortocoronary bypass grafts.

Adult↗