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Biomedical subjects

K Piters

Publications and source records attributed to K Piters.

2 recordsLinked to original sources

Ultrasonography in the detection of residual urine.

Eleven patients with distended urinary bladders (10 diabetics with autonomic neuropathy and one patient with prostatic hypertrophy) were examined by ultrasonography in an attempt to define the volumes detectable by this technique. Incremental volumes of saline were instilled through indwelling Foley catheters with ultrasonographic examination at each volume. The ultrasonograms obtained were presented to two radiologists trained in ultrasonography, who were asked to identify the presence of residual urine. There was 97% certainty of recognizing the presence of 100-cc residual volumes and 100% certainty of recognizing 150-cc residual volumes. It is concluded that residual urine volumes greater than 100 cc are clinically detectable by ultrasonography, a noninvasive alternative for diagnosing this common diabetic condition.

Adult↗

Chlorpropamide-induced hyponatremia.

A 29-year-old woman with severe idiopathic diabetes insipidus, while being treated by a combination of chlorpropamide and chlorothiazide, developed the syndrome of inappropriate secretion of ADH (SIADH) following an overdose of chlorpropamide. The syndrome resolved as the serum chlorpropamide level fell. This report demonstrates that a chlorpropamide-induced SIADH can occur in a patient with idiopathic diabetes insipidus, and it appears that the antidiuretic effect of the drug is dose-related.

Adult↗