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Biomedical subjects

K Precht

Publications and source records attributed to K Precht.

At least 55 records · Page 3Linked to original sources

[A comparison of cinoxacin and nalidixic acid in the treatment of chronic urinary tract infections].

A total of 60 patients with chronic urinary tract infections were included in this comparative study. 29 patients received cinoxacin and 31 nalidixic acid for a period of ten days. There were five therapy failures in the cinoxacin group and nine in the nalidixic acid group. Drug-related side-effects were reported by 11 patients in the cinoxacin group and by 13 patients in the nalidixic acid group. Gastrointestinal and central nervous disturbances were the adverse reactions which occurred most frequently. In all cases side-effects disappeared quickly after therapy was discontinued.

Bacteriuria↗

[Comparative studies of the efficiency of MLW-1.3 and 1.8-hollow fiber dialyzers].

Clinically contradictory results in the use of hollow-fibre dialysers with surfaces of 1.3 and 1.8 m2 prompted us to compare their efficiency under standard conditions. It was found that the efficiency does not increase proportionally to the enlargement of the dialyser surface. the reason for this is to be seen in: the supply of rinsing solution in the dialyser, blood flow, insufficient degassing, coating of the membrane with denatured protein and, last but not least, the body mass of the patient himself. For optimum dialysis an individually suited dialysis time can be calculated from these data for each patient.

Body Constitution↗

[Treatment trials with hemofiltration/hemodialysis in pernicious catatonia].

Two juvenile patients affected for the first time with pernicious catatonia were treated repeatedly with combined hemofiltration and hemodialysis. During the first two or three sessions, the distinct psychopathological improvement only persisted during the session itself and in a lesser degree during the following hours. It was only after further treatments that the therapy effect lasted longer and passed over into a continuous remission tendency. The findings might support a toxin hypothesis (in a broad sense) with respect to the genesis of catatonia and encourage a continuation of the studies.

Adolescent↗

On the pyridoxal-5'-phosphate stimulation of aspartate aminotransferase and alanine aminotransferase in serum and erythrocytes of patients undergoing chronic haemodialysis and with kidney transplants.

Aspartate aminotransferase (AST) determinations in erythrocytes of patients undergoing chronic haemodialysis and with kidney transplants showed that patients receiving vitamin B6 had a smaller relative stimulation rate of AST by pyridoxal-5'-phosphate (P-5-P). In contrast to these results in erythrocytes, the apoAST and apo-alanine aminotransferase (ALT) activities in serum were increased in patients as compared with those of healthy persons. The corresponding relative stimulation rates of AST and ALT by P-5-P addition to the reaction mixture were not changed in the haemodialysis patients, but in renal transplant recipients the relative stimulation rate of AST was significantly smaller and that of ALT was greater.

Alanine Transaminase↗

[Homologous umbilical vein and vena saphena transplants as possible means of vascular access in chronic hemodialysis].

For a patient in the chronic programme of haemodialysis an uncomplicated accession to the vessels is the prerequisite for an optimum medical and social rehabilitation. Each form of a subcutaneous arteriovenous fistula is to be preferred to an epicutaneous shunt prosthesis. The percutaneous puncture of large vessels is necessary for the rapid connection to the dialyses in acute situations. In long-term treatments often all autologous accessions to the vessels are used up. Homologous substitution material for vessels is increasingly used also in patients ongoing dialysis. Apart from the methods for gaining homologous material is reported on first experiences in the application of homologous grafts of the umbilical vein and of a homologous vena saphena graft in patients undergoing dialysis.

Humans↗

[Chronic pyelonephritis from a clinical viewpoint].

The chronic pyelonephritis is an unspecific, bacterial, focal, interstitial nephritis with faculative participation of the pyelon. It is differentiated between an obstructive (secondary) and non-obstructive (primary) form. It is referred to the importance of risk factors and risk groups deriving themselves from this. Without doubt, the chronic pyelonephritis is the most frequent renal disease which is confirmed by new statistics of morbidity. The diagnostics still renders difficulties. In a course poor in symptoms it is not thought of the existence of the disease. For the rational dignostics in practice a step plan is recommended. In every case diagnostics should precede therapy. A therapeutic nihilism is to be avoided. A schematic treatment used without criticism and without taking into consideration individual peculiarities, secondary diseases, pregnancy and so on is to be abandoned. Short-term therapy and long-term prevention must be tuned one to another and possibly rationally combined. A plan for the long-term control in the renal dispensary is proposed.

Aftercare↗

Lecithin: cholesterol acyltransferase activity, HDL-cholesterol and apolipoprotein A in serum of patients undergoing chronic haemodialysis.

In comparison with a control group, significantly lower lecithin:cholesterol acyltransferase activities and HDL-cholesterol values were found in the serum of patients undergoing chronic haemodialysis, while apolipoprotein A concentration remained unchanged. Reduced activity of lecithin:cholesterol acyltransferase is an indication of the abnormal cholesterol metabolism in haemodialysed patients and could be, in addition to other factors, an explanation for the high incidence of cardiovascular diseases in this patient group.

Apolipoproteins↗

[Urinary tract infections in gynecology and obstetrics].

Against the background of more recent insights into the general importance of urinary infections, specific reference is made to the demands made, in that context, on gynaecology and obstetrics. An attempt is made to expound the epidemiological chain of causes, ranging from defloration cystitis and including gestational processes as well as all sorts of gynaecological effects up to possible diseases in the menopause. The high probability of secondary diseases in adult age should be the point of departure for conclusions regarding "prophylaxis". Description of a stepwise programme for diagnosis, therefore, is followed by discussion of aspects relating to urine collection, differentiation between significant bacteriuria courses, assessment of asymptomatic bacteriuria, distribution of germs, and demands on monitoring action. Therapies are discussed separately for gynaecological patients and pregnant women. In conclusion, major emphasis is laid on the need for taking widest possible advantage of advisory centres for pregnant women and contraception consultative services for early detection of renal diseases and hypertension as well as for more efficient follow-up or extended medical care for patients whose urinary infections has been (re)discovered and treated by obstetricians or gynaecologists.

Adolescent↗

Creatine kinase isoenzyme BB in serum of patients undergoing chronic hemodialysis and with kidney transplant.

The activity of creatine kinase isoenzyme BB (CK-BB) was determined in serum of healthy adults and in patients undergoing maintenance hemodialysis and with kidney transplant. In the healthy adults examined, an activity of 0.56 +/- 0.16 U/l (mean +/- SD) was found. The arithmetic mean of CK-BB activity in patients with renal insufficiency under hemodialysis was 1.42 +/- 0.87 U/l and differed from that of the healthy group. The CK-BB activity in patients with kidney transplant was not different from that of the control group. The occurrence of CK-BB in serum is discussed from diagnostic and methodological point of view.

Adult↗

[Haemodialysis in patients with pre- andpostoperative acute renal failure (author's transl)].

Treatment and management of patients with renal insufficiency before and after surgery is often complicated. Early interdisciplinary cooperation between intensive care specialist, surgeon, gynaecologist, urologist and nephrologist is necessary. The mortality rate of patients with acute renal failure is still high (50 to 60%). The increase in patients with chronic renal failure who are in need of haemodialysis involves more surgical procedures in this group even in future.

Acute Kidney Injury↗

[Effect of chemotherapy on kidney function in pyelonephritis due to calculi with kidney insufficiency].

In patients with stone pyelonephritis the behaviour of the renal function under the influence of chemotherapy was examined at the stage of the compensated retention. 24 cures carried out on clinical conditions on 10 patients with an average age of 52 years (14--71) were evaluated. By means of chemotherapy in connection with the treatment of anaemia and the compensation of acidosis the renal function could favourably be influenced and the terminal stage of the renal insufficiency could be shifted. The author adopts a definite attitude to the long-term prophylaxis.

Adolescent↗

[Laboratory diagnosis in kidney- and bladder diseases].

The laboratory diagnostic spectre in diseases of the kidneys and the urinary bladder is demonstrated in form of a 3-step-programme. The concentration of suitable investigation methods in complexes allows a rational and economical diagnostics for patient and physician. A standardisation of the diagnostics in out-patient department and clinic essentially contributes to the reduction of excessive work in overcharged laboratories as well as to the shortening of the patient's stay in the hospital.

Angiography↗

[Studies of disinfection of hemodialysis instruments].

Fever reactions in dialysis patients may partly be traced back to the transmission of pyrogens from the rinsing solution compartment into the sanguiferous system. The pyrogen concentration increases with the germ contents of the rinsing solution, which, therefore, should be kept as low as possible by suitable desinfection measures. For the artificial kidney Gambro AK 3 a hot water desinfection of 90 minutes at 90 degrees C or a formalin desinfection of 30 minutes, respectively, for the artificial kidney Leuven IIIC the formalin or peracetic acid desinfection of 30 minutes each proved to be sufficient.

Acute Kidney Injury↗

[Functional and urinary analysis diagnosis of pyelonephritis].

For the practicing physician pyelonephritis is a frequently observed clinical picture which still has its diagnostic problems. With the help of a step programme a reasonable diagnostics is striven for which gives the possibility of an early recognition in the general surgery and a far-reaching clarification of the clinical picture in the out-patient department.

Chronic Disease↗