Biomedical subjects

K R Dwyer

Publications and source records attributed to K R Dwyer.

2 recordsLinked to original sources

PubMed1981

Black pigment or polybilirubinate gallstones: composition and formation.

Black pigment, extracted from gallstones from patients, has been characterized as polybilirubinate. A similar material with the same physical properties was synthesized from bilirubin. The properties of black pigment are described. A mechanism for black pigment formation is postulated, and the possible relationship of this pigment to the formation of gallstones is discussed.

Bilirubin↗

PubMed1979

In vitro studies of gallstone dissolution using the scanning electron microscope.

Scanning electron microscope studies on cholesterol gallstones, which had been subjected to, but had not been completely dissolved by, chenodeoxycholate and deoxycholate salts, have indicated the presence of an insoluble organic matrix, probably a mucopolysaccharide. Solution of a gallstone in vitro is enhanced by the addition of heparin which dissolved this matrix, thus allowing complete dissolution of cholesterol in a gallstone.

Chenodeoxycholic Acid↗