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Biomedical subjects

K R Gupta

Publications and source records attributed to K R Gupta.

At least 19 recordsLinked to original sources

Bulimic disorders and sociocentric values in north India.

BACKGROUND: Previous studies have shown low rates of eating disorders in some developing countries. We set out to investigate the prevalence of bulimia in an all-female college population in north India and relate it to sociocentrism of the culture. METHODS: A total of 504 students in an all-girls private college in an industrial town in north India completed the Hindi translation of the Bulimia Investigatory Test, Edinburgh (BITE). A random sample of 50 students, irrespective of their scores, were interviewed using the DSM-III-R interview for eating disorders; they were also asked about qualitative aspects of their relationship with the family and their own views of their identity. RESULTS: There was no effect of age, social class, religion or height on the distribution of BITE scores. Three key factors emerged; these were related to the constructs of compulsive activity, impulsivity/sociocentric avoidance and associated attitudinal responses and depressive thinking with features of helplessness and feelings of failure. Acculturation was not related to BITE scores. Virtually all interviewees had sociocentric views of theirselves. CONCLUSIONS: Sociocentrism and impulsivity account for a significant amount of the variance. The role of sociocentrism in influencing patterns of eating deserves to be studied further.

Acculturation↗

Copper levels & reactive oxygen species in uterine flushings in copper intrauterine contraceptive device users.

Copper levels were estimated in the uterine flushings in 15 copper 'T' 200 device acceptors. There was a statistically significant difference in the preinsertion and one week post insertion values (P < 0.001). This also corresponded to a high level of generation of reactive oxygen species. The levels of reactive oxygen species were similar to preinsertion values at 4 and 12 wk. The copper values declined over the 3 months but were still higher at 12 wk as compared to preinsertion levels and this difference was statistically significant. Hence addition of copper to the intrauterine device besides enhancing the contraceptive efficacy, perhaps also plays an important role in microbicidal activity and helps in overcoming the infection introduced at the time of insertion.

Adult↗

Levels of copper and zinc in depression.

The study was undertaken to estimate plasma copper and zinc in thirty-five depressed patients. Two blood samples were drawn from each patient, one before starting treatment and the second after recovery from depression. The results were compared with the thirty-five normal healthy individuals. The mean plasma copper in controls, depressed patients and in patients after recovery were 106.82, 122.14 and 104.22 micrograms/dl, respectively. The copper levels in patients when depressed were significantly higher as compared to controls and after recovery from depression. The mean plasma zinc levels in controls, depressed patients and after recovery were 115.80, 107.62 and 125.68 micrograms/dl, respectively. No significant difference could be obtained between control and depressed patients. However, the values were significantly higher in recovered patients compared to patients with depression.

Copper↗

Self-limiting acrodermatitis enteropathica. A follow-up study of three interrelated families.

A variant of acrodermatitis enteropathica is described that has its onset before weaning and clears when the child starts its normal solid diet. A pedigree with three interrelated families is reported where 10 children were afflicted with this variant. They had symptoms of hypozincemia for a brief period during infancy. At the time of this study, they were symptom-free and their serum zinc levels were found to be within normal limits. The term "self-limiting acrodermatitis enteropathica" is proposed for the variant. In one lactating mother, the mammary zinc secretion was determined and was found to be deficient and unresponsive to oral zinc supplements. The possible mode of inheritance is also discussed.

Acrodermatitis↗

Hamartoma of nasopharynx.

The extreme rarity of nasal and nasopharyngeal hamartoma, and its possible confusion in early diagnosis, prompted us to undertake a brief review of hamartomatous masses in E.N.T. practice along with this case report.

Adult↗