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Biomedical subjects

K R Hanes

Publications and source records attributed to K R Hanes.

13 recordsLinked to original sources
PubMed2005

Temporomandibular disorder subtypes according to self-reported physical and psychosocial variables in female patients: a re-evaluation.

Several studies support the relevance of psychological and psychosocial factors in the assessment and management of chronic musculoskeletal pain disorders, including temporomandibular pain disorders (TMDs). The aim of this study was to re-evaluate subtyping approach used in an earlier study (TI Suvinen, KR Hanes, JA Gerschman, PC Reade. J Orofac Pain 1997;11:200) and to compare perceived physical symptoms, psychological, coping and psychosocial variables between subtypes of patients who seek treatment for their temporomandibular pain and dysfunction. A total of 41 consecutive female patients were assessed multiaxially for physical symptoms, coping style and effectiveness and illness behaviour by a previously validated Temporomandibular Pain Dysfunction Questionnaire (TI Suvinen, KR Hanes, JA Gerschman, PC Reade. J Orofac Pain 1997;11:200). Additional measures of psychosocial variables included the global scores of the Beck Depression and Anxiety Inventory and Part I of the Multidimensional Pain Inventory. Subtypes were generated using an iterative partitioning method, k-means cluster analysis. Three clusters were identified and termed as Simple (22%), Intermediate (41%) and Complex (37%) temporomandibular disorders subtypes. Significant differences (P < 0.05) were found between clusters in psychological (coping style and effectiveness, disease conviction and affective disturbance) and in psychosocial variables (daily interference and social, work and family satisfaction), but not between physical variables. The results support previous studies that have shown differences in psychosocial variables in the presentation and subtyping of TMDs and the biopsychosocial orientation in assessment. The findings need to be reverified in a larger sample along specific physical diagnoses, but it is tentatively proposed how the three subtypes could be used in the classification of temporomandibular pain patients to guide management, based on the constellation of predominant psychological and psychosocial illness impact variables.

Adaptation, Psychological↗
PubMed1998

Neuropsychological performance in body dysmorphic disorder.

Fourteen patients with body dysmorphic disorder (BDD) were assessed with neuropsychological measures, including tests of executive, mnestic, and motor functions. Performance in these patients was compared to 10 patients with obsessive-compulsive disorder (OCD), 14 patients with schizophrenia, and 24 normal controls. Findings indicated normal performance of the BDD group on measures of mnestic and motor function, but poor performance of this group on tests of executive function (p < .05). The overall performance of the BDD and OCD groups on the neuropsychological measures was similar, while the schizophrenic groups showed a wider spectrum of neuropsychological deficits to these groups. These findings are discussed in terms of current theories of executive functions and the possible relationship between BDD and OCD.

Adult↗
PubMed1997

Outcome of therapy in the conservative management of temporomandibular pain dysfunction disorder.

The present study considered predictors of the outcome of treatment for temporomandibular pain dysfunction disorder (TMPD). Thirty-seven patients were assessed with objective and self-report measures of physiological and psychosocial aspects of this disorder at initial assessment and at 6-month follow-up subsequent to conservative physical therapy. Patients were subdivided into slow and rapid responders to conservative physical therapy based on self-reported level of improvement. Measures employed included the Temporomandibular Pain Dysfunction Disorder Questionnaire and the Temporomandibular Pain Dysfunction Disorder Clinical Form. Eighty-one per cent of patients showed a 50% or greater improvement in pain severity at follow-up, with minimal differential changes across the two groups found in the physiological symptoms, while the rapid responding group showed greater improvement in terms of psychosocial factors. These findings indicated that psychosocial factors, particularly coping strategies and illness behaviour, cannot be ignored in the management of TMPD.

Adaptation, Psychological↗
PubMed1997

Psychophysical subtypes of temporomandibular disorders.

This study presents an approach to the classification of temporomandibular disorders (TMD) based on acknowledgement of the interaction of physical, psychologic, and social factors using a multidimensional instrument that has been previously validated. The psychometric properties of this instrument were reevaluated in 140 women with TMD. Multidimensional clustering identified three subgroups of patients with TMD, including a highly distressed, psychosocially maladaptive group; a moderately distressed, behaviorally functional group; and a predominantly physical disorder group with an unremarkable psychosocial profile. These groups were termed maladaptive, adaptive, and uncomplicated, respectively, according to the constellation of predominant symptoms and psychosocial profiles of each cluster. The groups showed no consistent differences in pain frequency, use of medication, or duration of pain. This finding supports earlier work that suggested the prominence of three subtypes of this disorder according to both physical illness and psychosocial illness impact parameters.

Activities of Daily Living↗
PubMed1996

Brief report: bradyphrenia in Parkinson's disease, Huntington's disease, and schizophrenia.

The current paper assessed bradyphrenia, or slowed thinking, in patients with Parkinson's disease, Huntington's disease, and schizophrenia using a modified planning measure designed to maximise the demands on cognitive processing. Findings indicated normal performance in schizophrenia but prolonged thinking time in Parkinson's disease and, to a lesser degree, Huntington's disease and a relationship between thinking time and task complexity.

Journal Article↗
PubMed1996

Subcortical dysfunction in schizophrenia: a comparison with Parkinson's disease and Huntington's disease.

Neuropsychological performance in 20 chronic schizophrenic patients was contrasted to 25 Parkinson's disease, 12 Huntington's disease patients and 26 normal controls on measures shown to be sensitive to subcortical dysfunction. Some overlap was observed in the performance of the schizophrenic and basal ganglia groups on tasks of executive and mnestic function, but the general pattern indicated significant differences in performance. Notably, in contrast to the two basal ganglia groups, there was no evidence of slowed thinking, or impaired motor function in schizophrenia, which are considered hallmarks of subcortical grey matter disease. An association was observed between poor performance on the tests of executive function and the severity of negative symptoms. Our findings suggest that schizophrenia is not associated with primary subcortical impairment, but is more likely to reflect frontotemporal dysfunction. We consider that the similarities between this disorder and subcortical degenerative syndromes may be due to a difficulty in generating action in schizophrenia, perhaps arising from dorsolateral prefrontal disconnection.

Adult↗
PubMed1996

A brief assessment of executive control dysfunction: discriminant validity and homogeneity of planning, set shift, and fluency measures.

The current study evaluated the discriminant validity and homogeneity of category fluency, Stroop interference, and planning measures of executive dysfunction and introduced a new measure of planning behavior. We compared performance of patients with schizophrenia, Parkinson's disease, and Huntington's disease, which are disorders associated with some impairment of executive function. Findings indicated that all three measures successfully discriminated between patient groups and controls. Correlational analysis suggested a strong association between test scores on these measures, which were only moderately related to performance on nonexecutive function measures. It is concluded that the three tasks are sensitive and relatively homogeneous in their recruitment of executive functions.

Journal Article↗
PubMed1995

Cognitive flexibility and complex integration in Parkinson's disease, Huntington's disease, and schizophrenia.

Two new tasks designed to individualize and assess aspects of cognitive flexibility and complex integration were administered to patients with schizophrenia (n = 16), Parkinson's disease (PD; n = 25) and Huntington's disease (HD; n = 12). Findings indicated impaired performance in the schizophrenic and HD groups on components of solution fluency, reactive flexibility and integration. The PD group demonstrated normal performance on all but the solution fluency and reaction time measures. These findings corroborate previous studies suggesting that executive and problem solving disturbances feature in schizophrenia and HD and that these functions may not be as severely affected in medicated PD. Slowed reaction time by both dementia groups is explained with reference to the concept of bradyphrenia.

Adult↗
PubMed1995

Dysfluency in Huntington's disease, Parkinson's disease and schizophrenia.

Verbal fluency was compared in Huntington's disease (n=12), Parkinson's disease (n=25) and schizophrenia (n=18) with a series of fluency tasks evaluating the effects on productivity of cuing with subordinate categories and alternation between fluency probes. Findings indicated reduced output in the patient groups across all tasks consistent with a difficulty in intrinsic generation. A significant group interaction was observed with cue provision, but not with alternation. The facilitation of performance with cuing in all groups suggests a common mechanism of disruption in these disorders, most likely reflecting interruption of the prefrontal modulation of retrieval processes. To explain the observed pattern, we propose that the semantic retrieval anomaly in these disorders reflects a difficulty in intrinsic extra-dimensional shift. Verbal productivity was significantly associated with negative dimensions of schizophrenia, such as poverty of speech and flattened affect, a finding that is discussed in terms of the neurocognitive heterogeneity of schizophrenia and theories of cognitive dysfunction in subtypes of this disorder.

Journal Article↗