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Biomedical subjects

K R Springer

Publications and source records attributed to K R Springer.

6 recordsLinked to original sources
PubMed1991

Intraosseous lipoma of the calcaneus. A case report.

The intention of this report is to heighten the practitioner's clinical suspicion of intraosseous lipoma of the calcaneus. The apparent infrequency of this diagnosis may be attributed to the dependence on radiographic evaluation and the use of closed needle biopsy. Thus, to make a proper diagnosis, a computed tomography scan with the rate of attenuation and, ultimately, a large tissue biopsy with attentive gross and microscopic examination are necessary.

Biopsy, Needle↗
PubMed1982

Sex-limited genetic variation in a mouse salivary protein.

This report describes a gene which influences the electrophoretic mobility of a protein in the salivas of adult mice. Three categories of phenotype have been observed: the two single-banded types, F (Fast) and S (Slow), and the two-banded type, SF (Slow-Fast), with the two bands represented in varying proportions. All females, regardless of age or strain, and all males before puberty show only the F phenotype. Males of the BALB/c and C57BL/6J strains show the F phenotype throughout puberty and adult life, whereas males of the C3H/St and C57BL/KsJ strains show the SF phenotype in puberty and the S phenotype in adult life. We have designated this variation the sex-limited saliva pattern (Ssp). The results from genetic crosses indicate that the variation among the strains is determined by an autosomal locus, Ssp, with two alleles, SspS and SspF, where SspS is dominant to SspF. Testosterone treatment can accelerate the acquisition of the S type in males of the strains C3H/St and C57BL/KsJ and also induces that phenotype in C3H/St females and C57BL/6J males. Thus it appears that the observed strain-specific differences reflect a genetic variation in androgen levels and/or androgen sensitivity rather than variation in a structural gene.

Animals↗
PubMedDate not supplied

Flap coverage of a chronic hallux ulcer.

For nonhealing, noninfected plantar ulcerations of toes, flap coverage can be a viable alternative, providing there is adequate vascular supply to the digit. This article presents an interesting case, wherein the digital ulcer was covered with a flap from the same toe. The flapped area was then covered with a skin graft.

Aged↗
PubMedDate not supplied

Synovial chondromatosis.

Synovial chondromatosis is a benign problem of synovial tissue. It is thought to be induced by trauma and affects only one joint. These masses often cause articular damage. Treatment of choice is surgical excision.

Adult↗