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Biomedical subjects

K Röddecker

Publications and source records attributed to K Röddecker.

6 recordsLinked to original sources
PubMed1992

Arthroscopy of the knee in children and adolescents.

Arthroscopy of the knee was performed in 104 patients under 18 years of age, 41 in children (aged 8 to 15) and 63 in adolescents (aged 16 to 18). Most frequently lesions of the patella were found (in 45% of all diagnoses in children and 29% in adolescents), in most cases because of acute or recurrent dislocation of the patella. The incidence of meniscal lesions increased with age. The most frequent therapeutic procedure performed in children was a lateral release (34%), in adolescents a partial meniscal resection (31%). In children 43% of arthroscopies were diagnostic, in adolescents 21%. Preoperative diagnosis was shown to be incorrect or incomplete arthroscopy in 41% of children and 24% of adolescents taking arthroscopic findings as a golden standard. Preoperative diagnosis had highest accuracy for dislocation of the patella, 90% of dislocations were diagnosed correctly before arthroscopy. The lowest accuracy of clinical diagnosis was found for meniscal lesions; only 36% of meniscal tears were suspected preoperatively. In 35 of 38 patients with hemarthrosis a relevant knee lesion was found, in 23 of these patients arthroscopic therapy was performed. This justifies our concept for arthroscopy of every knee hemarthrosis. Besides superficial chondral lesions in 8 patients there were no complications associated with the procedure. It is concluded that arthroscopy of the knee in children and adolescents is a safe procedure with high diagnostic and therapeutic value.

Adolescent↗
PubMed1991

[Arthroscopic meniscus suture].

Up to the late 1970s meniscectomy was a common procedure in case of meniscus tear. After operative technique was improved with arthroscopy and the meniscus was accepted as an important structure in the knee joint, different techniques of arthroscopic meniscus repair were demonstrated. Thirty-two patients were reexamined 2-4 years after arthroscopic meniscal repair by means of a technique developed in Cologne. Traumatic capsular lesions healed well even in case of persisting instability to the knee joint.

Arthroscopy↗
PubMed1990

[Effect of different fibrin sealants on fibroblast activity in skin wounds. Experimental studies in rats].

The effects of two different fibrin sealants on synthetic activity of fibroblasts in incisional skin wounds of rats were studied by tracer experiments with 14C-proline. Additionally the wounds and the subcutaneous rests of the fibrin sealants were examined histologically. When the sealants were applied immediately after wounding there was no difference to untreated controls. However, administration on day 3 after injury resulted in a significant increase of 14C-incorporation by both preparations. This stimulation of synthetic activity after retarded treatment must be caused by the direct contact between the sealants with their soluble components and the fibroblasts, which are more frequent in the wounds on day 3. Differences between the two preparations could only be observed in the histological examination of the subcutaneous fibrin clots. Preparation 2 induced stronger encapsulation, cell invasion, and fibrinolysis of the clots than preparation 1.

Animals↗
PubMed1989

[The effect of subtherapeutic quantities of native gelatin and Haemaccel 35 (polygeline) on the fibronectin level and wound healing. An experimental animal study in rats with burn wounds].

Posttraumatically, opsonic plasma fibronectin is consumed by collagen-like degradation products that enter the vascular system. Additional administration of gelatin (= denatured collagen) results in an essential lack of fibronectin with subsequent retardation of wound healing even when subtherapeutic amounts are given. Therefore, in an experiment with rats we studied the question of whether similar effects are evoked by equal amounts of Haemaccel 35 (cross-linked polypeptides from degraded gelatin). The animals received standardized third degree burn injuries of about 1% of body surface. Immediately after wounding and on the following 2 days native gelatin or Haemaccel was applied intraperitoneally in 2 different dosages (61 mg/kg and 122 mg/kg). The burn injury by itself did not cause a significant decrease of plasma fibronectin. After injection of gelatin a dramatic deprivation of plasma fibronectin occurred and, in consequence, a delay of the healing process. After administration of equal amounts of Haemaccel 35, however, there was neither a depletion of plasma fibronectin nor any significant effect on wound healing.

Animals↗
PubMedDate not supplied

[Measurement of the biomechanical stability of the healing menisci in animals: fibrin gluing, an alternative to traditional therapy methods?].

Six weeks after spontaneous healing or suturing of standardized longitudinal lesions in zone II of the posterior horn of the rabbit medial meniscus there was no difference of any kind evident. After fibrin sealing, however, a significant higher stability of scar tissue was measured. Compared to intact menisci in all cases scar stability was diminished, hence in the elongation of the scar the tissue was also weakened. This region of weakness was significantly reduced in menisci that had been sealed. Due to these results it is of utmost necessity that the meniscus suture in zone II should be thoroughly reexamined; the application of fibrin sealant should be seriously considered.

Animals↗