Biomedical subjects

K Ravichandiran

Publications and source records attributed to K Ravichandiran.

2 recordsLinked to original sources

PubMed1996

Blood lipid changes in repeated infections of vivax malaria.

Alterations in the levels of plasma and erythrocyte membrane lipids in fresh and repeated P. vivax malarial patients were studied. A significant fall in plasma cholesterol and phospholipids was observed in repeated malaria. The decrease was highly significant when the number of attacks were more than five (p < 0.0001). A significant increase in plasma triglycerides and non-esterified fatty acids were observed when the number of attacks was between 4-5 (p < 0.0001). Erythrocyte membrane cholesterol and phospholipids were increased in repeated malaria. The increase in erythrocyte membrane cholesterol and phospholipids, was significant in more than five attacks (p < 0.0001). The activities of LCAT and LPL were decreased significantly in repeated malaria, when the number of attacks were between 4-5 (p < 0.0001). It is suggested that repeated malarial attack alters the lipid metabolism and the changes are marked with increase in the number of malarial attacks.

Adolescent↗

PubMed1996

Liver function tests in recurrent P. vivax malaria.

Blood samples were collected from 61 P. vivax infected fresh and recurrent malaria patients and liver function parameters studied. Plasma albumin, A/G ratio were found decreased significantly (p < 0.001) when compared to controls. Among the group of recurrent malaria patients with more than five attacks lowest values were found and the decrease was directly correlated with the number of attacks. The enzyme activities of plasma LDH, SGPT and thymol turbidity were found increased significantly with the increase in the number of attacks (p < 0.001). The increase was more pronounced in more than 5 attack (R3) group. The levels of total, conjugated and free bilirubin and the enzyme activities of SGOT, alkaline phosphatase were also found increased significantly in all the recurrent malarial groups, when compared to controls, without any correlation between the number of attacks. The isoenzyme pattern of plasma LDH was not altered in either fresh or recurrent malarial attack groups when compared to controls.

Adolescent↗