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Biomedical subjects

K Reissmann

Publications and source records attributed to K Reissmann.

10 recordsLinked to original sources

[Thrombolytic therapy with special reference to old venous occlusions].

It is reported on own results and experiences in 53 thrombolyses with the streptokinase preparation Awelysin. In the greater part of the 46 patients with phlebothrombosis the cases in question were late thromboses (n = 32). In 7 cases an arterial lysis was performed. The author enters in detail the questions of dosage and side-effects as well as complications. By reason of the phlebographic and clinical findings before and after therapy also in older thromboses may be still reckoned with complete or extensive recanalisation in 65.5% and with a clinical symptom-free state in 71%. In comparison to reports on results in early lysis the findings got do not show essential deviations in late lysis.

Adolescent↗

[Determination of glycogen phosphorylase B--a contribution to the enzymatic diagnosis of acute myocardial infarct].

On the basis of a small number of patients with the tentative diagnosis acute myocardial infarction the diagnostic valency of the glycogen phosphorylase was tested. A separation between severe stenocardia and myocardial infarction is possible. After simplification of the methodology the glycogen phosphorylase might substitute in higher specifity the creatinine kinase.

Aged↗

[Value of lymphography within the framework of complex diagnosis of fever of unknown origin].

After comprehensive diagnostics on account of antibiotic-resistant subfebrile temperatures under suspicion of a lymphogranulomatosis a lymphography was performed in a 49-year-old patient. The lymphographic findings are discussed in detail. Since these findings differential-diagnostically allow a tuberculosis of the lymph nodes, a tuberculostatic therapy is performed. 6 months later the patient has an improved general condition and may again work in this former profession.

Diagnosis, Differential↗

[The antistreptolysin reaction with and without dextran sulfate addition in various diseases].

It is reported on the results of determinations of the antistreptolysin titre in patients with infectious hepatitis, renal and essential hypertension, mitral stenosis, acute tonsillitis, scarlet fever, rheumatic fever as well as rheumatoid arthritis according to the usual and the dextran sulphate absorption method in altogether 739 patients. Here as in a former publication in 1,700 normal persons partly considerable significant differences between the antistreptolysin titre with and without dextran sulphate were found. The two techniques are discussed, also the influence of the beta-lipoproteins with their proportion of phosphatide on the result of the antistreptolysin titre. It is possible to absorb beta-lipoproteins and perhaps also phosphatides with the help of the addition of dextran sulphate. The present investigations show unequivocally that the absorption the dextran sulphate is a necessary demand which saves the clinician from diagnostic and therapeutic errors. The antistreptolysin reaction is to be regarded only as one constituent for the clinical diagnosis and must not be overvalued in its importance.

Antigen-Antibody Reactions↗

[Antistreptolysin-titre under the use of traditional methods and after saturation with dextran sulfate].

1,700 blood samples of healthy test persons without clinically and paraclinically provable streptococcal diseases were examined for their content of antistreptolysin. Beside the usual method parallel determinations were carried out after addition of dextran sulfate. Thus increases of unspecific antistreptolysin titres shall be in most cases excluded, above all by the influence of the lipoproteins. The absorption of dextran sulfate led to the decrease of the antistreptolysin titre by 12.33%. Furthermore could be proved that the average antistreptolysin titre of female test persons is ca. 20 antistreptolysin units below the titre of male test persons, that seasonal variations of the antistreptolysin titre with the highest titres appear in the first and third quarter which may be explained by a bad unspecific defensive condition, that, furthermore, the antistreptolysin titres increase to the 14th year and then continuously decrease and that in new-born children the arithmetic mean value of the antistreptolysin units is significantly higher than in their mothers. Hereby an active influence of the placenta on the transmission of antibodies seems to be possible. Though a slightly increased financial expenditure is necessary for dextran sulfate, temporarily and concerning working technique, however, no larger loads appear, it is justifiable to perform the determination of antistreptolysin titres only by means of dextran sulfate-absorbed sera, since in this way a considerable number of unspecific and misleading reactions can be excluded.

Adolescent↗

[Immunosuppressive treatment of progressive chronic polyarthritis].

After description of forms and possibilities of the immunsuppression the results of this therapy are discussed in 47 own patients with clinically and paraclinically ascertained rheumatoid arthritis. The patients received the sum of 4.0 mg trenimon in combination with altogether 4.0 mg cyclophosphamide by means of 20 infusions with physiological saline solution as carrier substance. Under this treatment in 93.6% of the cases the findings of the examination of joints or the clinical stage improved. As to side effects incompatibilities on the side of the gastro-intestinal tract as well as leucopenias were observed. 18 patients could be after-examined after 6 years. Whilst in every case the clinical stage deteriorated, in the majority the degree of activity remained unchanged. All the results are compared with the results reported in literature. The authors are of the opinion that, when other forms of treatment have no success and contraindication are strongly taken into consideration, the progressing of the rheumatoid arthritis can be retarded by means of immunsuppressives. The pathophysiological processes can, however, scarcely be influenced causally.

Adult↗

[Old and new standardized color test for the determination of aspartate aminotransferase in the differential diagnosis of heart infarct and angina pectoris].

The usability of the new and old standardized colour test for the determination of the aspartate aminotransferase (GOT) (set of test instruments VEB Arzneimittelwerk Dresden) in the differential diagnosis between acute myocardial infarction and angina pectoris are compared. Concerning this problematics the new colour test does not evoke a better separation effect than the old one. Since with the change-over there were connected considerable uncertainties in the clinic it is recommended in case of a future standardisation to publish the regions of reference and first clinical experiences before the change-over.

Angina Pectoris↗