PubMed Health⌕ Search

Biomedical subjects

K Reist

Publications and source records attributed to K Reist.

6 recordsLinked to original sources

[Necrotizing fasciitis cause by beta-hemolytic streptococci with fatal outcome--a case report].

The authors report two cases of necrotizing fascilitis (NF) occurring after surgical interventions on the breast (reduction mammoplasty in one patient and mastectomy for breast cancer in the other). In both cases the etiologic agent were group A pyogenic streptococci and both patients died. NF caused by hemolytic streptococci is a highly lethal disease (over 70% in literature). It starts typically with a purple lesion of the skin, followed by necrotizing fascial infection with secondary necrosis of the overlying skin and rapid progression to septic shock and multiorgan failure. This development is characteristic for NF and allows, together with microbiological results, to distinguish NF from other necrotizing soft tissue infections. Early recognition and aggressive surgical debridement are the mainstays of successful management. Antibiotics and intensive care therapy are indispensable. Hyperbaric oxygen or other supportive therapies do not lower death rate.

Adult↗

[Sepsis score in surgical intensive care medicine].

In a prospective study (400 patients, intensive care stay > 18 h) the following data were documented daily: Clinical sepsis, a modified sepsis score, Apache II-score, number of organ failure, Elastase-concentrations and injury severity score (ISS > or = 20 = polytrauma). On admission day a prognostic assessment for early diagnosis of septic complications during intensive care could be demonstrated by a combination of the modified sepsis score and the number of organ failures and the presence of polytrauma. All other parameters did not have any predictive value.

APACHE↗

[Effect of Nutriflex 48 on the plasma amino acid pattern in surgical intensive care patients with infection].

Nutriflex 48 (48 g amino acids and 1250 nonprotein kcal/l), containing 20% branched chain amino acids, was infused in a dose of 2000 ml per day over a period of 14 days to 8 surgical intensive care patients with sepsis and concomitant liver dysfunction. Cumulative nitrogen balance was negative on each day of investigation, as aspected in those patients. The amino acid patterns in plasma showed increased concentrations of methionin, while the concentration of branched chain amino acids remained in the normal range until the end of the study. The concentration of plasma ammonium was always normal. These results seem to indicate that in septic patients a total parenteral nutrition with conventional amino acid solutions containing normal concentrations of branched chain amino acids, is possible. The results of the present study show that the necessity of parenteral nutrition in septic patients with highly branched chain amino acids can not be supported.

Abdomen↗

[The mouth-plate, an aid in respiratory treatment in intensive care units (author's transl)].

The mouth plate is a new auxiliary device used in respiratory therapy. It is applied to patients who cannot adapt to conventional mouth pieces owing to different anatomical-functional difficulties. Easy clinical application and the air tight effect of the mouth plate permitted efficient respiratory therapy with IPPB in 20 cases with the mentioned difficulties so that some would not need more invasive measures such as endotracheal intubation or even mechanical ventilation. Other possible application in the intensive care unit and also in emergency medicine are mentioned briefly.

Adolescent↗

[A system for "intermitten mandatory ventilation" (IMV) using the engström respspirators ER 200/300 (author's transl)].

At low financial and material costs conventional Engström-respirators (Types ER 200, 300) can be converted to make Intermittent Mandatory Ventilation (IMV) possible. These so converted respirators were examined when a group of patients in a surgical intensive care unit who had undergone mechanical ventilation for a longer period of time was weaned from the respirator. It could be shown that during the step-by-step weaning of these patients no significant changes appeared in the results of the blood gas analyses, which means that the patients' pulmonary function took over again gradually. Doubtlessly, the convertability of the Engström-respirator for IMV will help promote the weaning of patients with respiratory complications by this method.

Intensive Care Units↗