PubMed Health⌕ Search

Biomedical subjects

K Reuther

Publications and source records attributed to K Reuther.

16 recordsLinked to original sources

Repeated bladder distension by the Cystomat in the treatment of detrusor instability.

Treatment of idiopathic detrusor instability with drugs and prolonged distension of the bladder is often unsatisfactory. Some amelioration of symptoms has previously been described by using the Cystomat. The present study showed that 1 week's treatment with the Cystomat produced convincing subjective improvement as well as an increase in bladder capacity. The improvements were statistically significant and persisted for 3 months. Although the mechanism by which bladder distension exerts its effect is poorly understood, the technique of repeated distension offers an alternative in the treatment of patients with idiopathic detrusor instability.

Adult↗

Acute retention of urine due to benign prostatic obstruction treated with alpha-adrenergic blockers.

Bladder catheterisation is the usual treatment in patients with acute retention of urine due to prostatic hypertrophy. The interference is not without complications why medical treatment would be a progress. The prostatic gland has been found to contain alpha-adrenergic receptors, and it has been argued that some cases of acute retention of urine is caused by over-stimulation of the alpha-adrenergic receptors. In the present study we have investigated the effect of intravenously administered phentolamine ( Regitin ) in patients with acute retention of urine, due to prostatic hypertrophy, and find that the treatment is an alternative to conventional bladder catheterisation.

Acute Disease↗

Alpha-adrenergic blockade in the diagnosis of detrusor instability secondary to infravesical obstruction.

Detrusor instability secondary to infravesical obstruction is probably caused by overactive stretch receptors in the bladder wall. Since recent studies have shown that alpha-adrenergic blockade with phenoxybenzamine reduces the intravesical pressure under micturition, we undertook this investigation in order to see if phenoxybenzamine has an effect on detrusor instability caused by infravesical obstruction. We found that the detrusor instability was abolished by phenoxybenzamine, which supports the 'stretch receptor theory'. Further, phenoxybenzamine is probably a good test in the diagnosis of detrusor instability secondary to infravesical obstruction.

Aged↗

Lignocaine test and detrusor instability.

Detrusor instability in infravesical obstruction is well recognised and often resolves after surgery. The aetiology is not clearly understood but is probably due to increased vesical sensory input. Since intravesical lignocaine has been proved to have an effect (although shortlived) on detrusor instability in some patients, we have used it in order to differentiate between idiopathic detrusor instability and detrusor instability caused by infravesical obstruction. Our study showed that in patients with a positive lignocaine test pre-operatively, the detrusor instability and micturition disorder disappeared after operation, and in patients with a negative lignocaine test, it persisted. The differences were statistically significant (P less than 0.5).

Aged↗

A comparison between the combination emepronium bromide/flavoxate and emepronium bromide in the treatment of detrusor instability.

Emepronium bromide and flavoxate have both and separately been used with success in the treatment of detrusor instability. In this study we have combined the two drugs emepronium bromide and flavoxate and compared the results with emepronium bromide. 20 consecutive patients with an uninhibited bladder, 12 men and 8 women, were randomly allocated to treatment with either emepronium bromide/flavoxate or emepronium bromide. In this trial we found that treatment with the combination is significantly better than treatment with emepronium bromide only.

Adult↗

Improvement of detrusor instability following repeated bladder distension with cystomat. A case report.

Treatment of idiopathic detrusor instability with drugs and prolonged distension of the bladder is often unsatisfactory. Some amelioration of symptoms was previously described after 24-hour bladder distension with use of the cystomat. A case is presented in which detrusor instability was successfully treated with continuous infusion via the cystomat, and thereby repeated bladder distension, for one week. The symptoms subsided, the cystometric bladder capacity was increased and there was no side effects. The improvement has persisted for six months. Though the mechanism by which the bladder distension exerts its effect is poorly understood, the technique of repeated distension offers an alternative in the treatment of patients with idiopathic detrusor instability.

Aged↗

Ruptured achilles tendons treated surgically under local anaesthesia.

Twenty-two patients with rupture of the Achilles tendon were successfully treated by simple end-to-end suture under local anaesthesia. The results are discussed in the light of previous literature on surgical versus conservative treatment and the advantages of surgery under local anaesthesia are pointed out.

Achilles Tendon↗