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Biomedical subjects

K Roed-Petersen

Publications and source records attributed to K Roed-Petersen.

At least 19 recordsLinked to original sources

Clinical assessment of the anal continence plug.

Recently, promising results with different modifications of an anal continence plug were reported in a pilot study. We have performed a clinical assessment of the plug preferred by the majority of patients in this study in an ambulatory group of patients incontinent to liquid and solid stool. Nine of 14 patients (64 percent; 95 percent confidence interval: 35-87 percent) were continent when they used the plug. In 43 percent (18-71 percent), the plug occasionally slipped out, and 71 percent (42-92 percent) experienced discomfort to a varying degree, which caused 11 patients to withdraw from the study before the end of the planned study period. No correlation was found between the results of anorectal physiology studies and the benefit or inconvenience of using the plug. The overall conclusion is that the majority of patients would use the plug under special circumstances because it eliminates the fear of fecal leakage but that local discomfort, possibly due to the material, would prevent its daily use.

Adult↗

Morbidity after immediate and delayed opening of sigmoid end colostomy: a randomised trial.

OBJECTIVE: To see if sigmoid end colostomies that were opened immediately carried a higher early morbidity than those in which opening was delayed for 10 days. DESIGN: Randomised trial. SETTING: University department of surgical gastroenterology. SUBJECTS: All patients for whom a temporary or permanent end sigmoid colostomy was done between December 1986 and May 1989. INTERVENTIONS: 51 patients had their colostomies opened immediately, and in 49 opening was delayed. MAIN OUTCOME MEASURES: Presence of ischaemia, retraction, separation or infection, and length of stay in hospital. RESULTS: Two patients from each group died within the first week; none of the deaths was associated with complications of the colostomy. One patient whose colostomy had been opened immediately developed gangrene of the stoma, and one in whom the opening had been delayed developed retraction. There was no difference between the groups in length of stay in hospital. CONCLUSION: As we could find no differences in morbidity whether the colostomy was opened immediately or whether it was delayed, we now recommend that it should be done immediately. The question of late complications (stenosis and hernia), however, cannot be answered yet.

Cause of Death↗

[Anal incontinence--pathophysiology and treatment].

The prevalence of anal incontinence is probably far greater than has hitherto been admitted. As a result of the appearance, and the knowledge of new methods of treatment an increasing number of patients seek help for this, often socially crippling, condition. The pathophysiology, the methods of investigation, and the possibilities of treatment, chiefly based on the author's own studies, are described in this review article.

Adolescent↗

Control for recurrences of urinary bladder tumours by transabdominal ultrasonic scanning.

By transabdominal ultrasonic scanning of the filled bladder it is possible to examine the surface of the bladder urothelium in the outpatient clinic. In a "blind" study of 129 patients controlled for recurrences of urinary bladder tumours the results of dynamic transabdominal ultrasonography were compared with the results of cystoscopy. The ultrasound could identify the recurrences of 5 mm or above in size significantly. Below 5 mm in dimension, when positioned in the dome of the bladder or at severe trabeculation the ultrasonic scanning lead to a misdiagnosis. No invasive recurrences were overlooked by ultrasonography. We will advocate that transabdominal ultrasonic scanning replace routine cystoscopy in low-risk patients with superficial bladder tumours of the Ta category and a low grade after the primary transurethral treatment and no or few recurrences of the same Ta category at the first control cystoscopy. On the other hand we will recommend to continue cystoscopy of patients with frequently recurring urinary bladder tumours, the high grade Ta tumours, carcinoma in situ because of the risk of invasive growth, and patients with primary invasive tumours including those with the superficial invasion (category T1).

Adult↗

The surgical treatment of mixed phosphatic renal lithiasis. Long-term follow-up.

Of a total of 36 patients operated on for mixed phosphatic renal lithiasis without renal cooling, 26 were re-examined after a mean postoperative interval of 51 1/2 months. Pelvic and calyceal stones had been present in 17 of these patients and staghorn stones in 9. All the patients had presented with persistent urinary tract infection. The total of kidneys operated on was 41. Examination 1 to 3 months after the operation showed complete stone clearance in 85% of these kidneys nd freedom for urinary tract infection in 78% of the patients. At long-term follow-up 73% of the patients had no urinary tract infection. The follow-up investigation suggest that tiny fragments of stone may be left in difficult operations, since such fragments do not necessarily lead to formation of new stones and are not necessarily accompanied by persistent urinary tract infection.

Adult↗

The pharyngo-oesophageal sphincter after laryngectomy. A manometric investigation.

The function of the pharyngo-oesophageal sphincter in patients subjected to total laryngectomy has been evaluated by manometric measurement, and the results related to the patient's ability to speak with an oesophageal voice, as well as to the occurrence of dysphagia. Seventeen totally laryngectomized patients were studied. The intelligibility of the patient's oesophageal voice was classified according to the scale: good (group IV), middle (group III), poor (group II) and unintelligible (group I). The manometric investigation was carried out with a continuously perfused low compliance system with three side holes, and the results of the patient investigation were compared with those from a normal material. It was possible in three patients only to demonstrate a resting tone corresponding to the pharyngo-oesophageal sphincter. The pressure was lower in these patients than in the normal material. No correlation was found between any of the three parameters: sphincter pressure, intelligibility, and the presence of dysphagia.

Adult↗