Biomedical subjects

K S Briggs

Publications and source records attributed to K S Briggs.

4 recordsLinked to original sources

PubMed1992

Intraocular pressure-related pattern of optic disc cupping in adult glaucoma patients.

The pattern of glaucomatous optic disc cupping was investigated in 67 eyes of 67 primary open-angle glaucoma patients with early-to-moderate visual field loss and a wide range of intraocular pressure. We determined the position of the deepest point of the optic disc cup using the Rodenstock Analyzer. This position correlated significantly with intraocular pressure: the deepest point tended to be located below the center of the optic disc at high intraocular pressure and above the center at low intraocular pressure. There was no significant correlation between the position of the deepest cup point along the horizontal axis and intraocular pressure. The position of the deepest point of the cup also correlated significantly with the severity of glaucoma, albeit less strongly than with intraocular pressure: it tended to be in the inferior portion of the disc at an early stage of glaucoma and in the superior portion of the disc at a more advanced stage of glaucoma. Therefore, the inferior portion of the optic nerve head appears to be most yielding to changes of intraocular pressure. These findings are consistent with histologic evidence of the least connective tissue support in the inferoperipheral region of the lamina cribrosa and with greater prevalence of inferior rim loss and corresponding superior visual field defects in early to moderately advanced primary open-angle glaucoma patients.

Aged↗

PubMed1991

Pattern of publication of ophthalmic abstracts in peer-reviewed journals.

Presentation of research work at scientific meetings and professional societies is an important first step toward effective scientific communication of research results. To determine the current publication patterns of abstracts, a computerized MEDLINE literature search was performed on 175 randomly selected ophthalmic clinical and basic science abstracts published in conjunction with two ophthalmic national meetings. This search revealed that 105 abstracts (60%) led to full-length articles in peer-reviewed journals within 50 to 56 months of the meeting date. A median interval of 13 months occurred from date of abstract publication to acceptance of the corresponding article. Most articles appeared within 3 years of abstract presentation. Sixty-four percent (48 of 75) of the posters and free papers presented at the annual meeting of the American Academy of Ophthalmology in November 1984 led to full-length articles, as did 57% (57 of 100) of the abstracts presented at the annual meeting of the Association for Research in Vision and Ophthalmology in May 1985. These findings emphasize the preliminary nature of abstracts. The fact that nearly 60% of abstracts are published reflects favorably on the review process of both meetings.

Abstracting and Indexing↗

PubMed1989

Reversal of glaucomatous optic disc cupping in adult patients.

A prospective study of reversal of glaucomatous optic disc cupping was performed by topographic optic disc analysis using the optic nerve head analyzer (Rodenstock analyzer, G. Rodenstock Instrumente GMBH, Munich, West Germany) in 13 adults with chronic open angle glaucoma. Intraocular pressure decreased from the mean (+/- SD) initial intraocular pressure of 33.2 +/- 8.2 mm Hg to the final intraocular pressure of 16.9 +/- 6.1 mm Hg over 13.6 +/- 10.4 weeks. Mean (+/- SD) cup-disc ratio decreased significantly, from 0.573 +/- 0.207 to 0.499 +/- 0.198, and mean (+/- SD) neuroretinal rim area increased significantly, from 0.913 +/- 0.341 to 1.042 +/- 0.284 mm2. The decrease of mean (+/- SD) cup volume from 0.592 +/- 0.966 to 0.451 +/- 0.703 mm3 was only marginally significant. However, more meaningful was a finding that reversal of cup volume, like reversals of cup-disc ratio and rim area, was directly proportional to the percent IOP reduction (r = .669 for cup volume reversal; r = .626 for cup-disc ratio reversal; and r = .675 for rim area reversal).

Adult↗

PubMed1986

Spasmus nutans: a pediatric enigma.

Spasmus nutans is an unusual neuro-ophthalmologic syndrome that affects infants. The clinical features of head nodding, nystagmus and head tilt are diagnostic although variability in their presentation is not uncommon. Computerized tomography of the head is recommended to rule out possible accompanying intracranial gliomas.

Brain Neoplasms↗