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Biomedical subjects

K S Liem

Publications and source records attributed to K S Liem.

6 recordsLinked to original sources
PubMed2001

[Boerhaave's syndrome: also in the emergency room].

Two men, aged 52 and 57 years, had vomited and then developed chest pain, dyspnoea and tachypnoea. After a myocardial infarction had been excluded in the cardiac emergency room, further examination revealed a rupture of the oesophagus. This was treated surgically with the ultimate creation of a tubular stomach. Both patients then recovered well. The Boerhaave's syndrome, a 'spontaneous' perforation of the oesophagus, is a rare and potentially lethal condition which should be diagnosed at an early stage. Pain in the chest, dyspnoea and vomiting are frequent symptoms. A cardiac cause is sometimes erroneously suspected. Subcutaneous emphysema is a major indication for a perforation of the oesophagus. The chest X-ray shows also mediastinal emphysema and infiltrative abnormalities; in case of doubt a second X-ray should be made some hours later.

Chest Pain↗
PubMed1984

Comparison of gastrointestinal blood loss induced by cloximate in two formulations and by naproxen.

In a double-blind baseline controlled crossover trial gastrointestinal blood loss induced by cloximate in two different formulations (enteric-coated and non-enteric coated) was compared with naproxen. Gastrointestinal blood loss increased more in the naproxen group (0.41 ml/24 h) than in the group treated with non-enteric coated cloximate. The group treated with coated cloximate had a higher mean increase in gastrointestinal blood loss (0.36 ml/24 h) compared with placebo than those treated with non-coated cloximate.

Acetates↗
PubMed1975

Immunization schedules for influenza.

Although on an individual basis and for some selected closed groups immunization against influenza has proved its value over the last 30 years, it has not resulted in prevention of epidemics. The impact of vaccination on national morbidity and mortality statistics has been disappointing. The reasons for this apparent failure of disease control by immunization are discussed. It is concluded that influenza vaccination has not been practised on a large enough scale to achieve an obvious effect on the spread of the viruses in open communities. The groups of people who deserve special attention in order to minimize the damages caused by influenza epidemics are considered. Advantages and disadvantages of available types of vaccine, methods and routes of administration are assessed. It is suggested that systematic application of present knowledge would probably have more impact in the near future than efforts to increase vaccine efficacy. The main current deficiencies are identified as the difficulty of producing adequate supplies of properly constituted vaccines at short notice and the general reluctance to accept annual large-scale immunization programmes. In the view of the authors these logistic and administrative problems could be resolved by long-term coordinated planning between relevant authorities and vaccine manufacturers.

Administration, Intranasal↗