PubMed Health⌕ Search

Biomedical subjects

K S Ratnakar

Publications and source records attributed to K S Ratnakar.

At least 19 recordsLinked to original sources
PubMed1991

Diagnostic utility of fine-needle sampling without aspiration: a prospective study.

Fine-needle sampling without aspiration (FNS) was done in 100 consecutive patients with 109 palpable masses. Its efficiency in obtaining adequate material is compared with conventional fine-needle aspiration cytology (FNAC) and found to be 80% with either method. FNS shows a diagnostic accuracy that correlates well with FNAC and histopathology. Malignant lesions are sampled more easily. Anatomic site has no influence on the yield. Most of the negative cases are small swellings, less than 1.5 cm in diameter. It is more cost effective than FNAC. Trauma to the tissues and the resultant artifacts are less. It is relatively painless and can safely be applied to many areas, including some sensitive sites.

Adolescent↗
PubMed1991

Mitral valvular stromal degeneration.

A 35-year-old female who presented with features of mitral valve disease showed mitral stromal deposits which were acidophilic in nature and brilliantly red by Masson trichrome. Stromal GAG (glycosaminoglycan) alterations are considered responsible for the deposits.

Adult↗
PubMed1990

Anaplastic astrocytoma of the spinal cord presenting with features of raised intracranial pressure.

Intramedullary tumors of the spinal cord in childhood are usually of low grades (grades I and II) and are most commonly seen in the cervical and cervicothoracic regions. They present with symptoms and signs of spinal cord tumor. It is uncommon to find an anaplastic astrocytoma situated in the thoracolumbar segment of the spinal cord. Whereas papilledema and raised intracranial symptoms have been reported in about 12.5% of cases of spinal cord tumors it is rare to find them presenting initially only with symptoms of raised intracranial pressure and only later followed by spinal cord symptoms. The case of an 11-year-old female child is reported here because of a combination of these two rare features.

Astrocytoma↗
PubMed1990

Posterior mediastinal paravertebral hydatid cyst presenting as spinal compression. A case report.

A primary posterior mediastinal hydatic cyst presenting with spinal compression syndrome is rare. We describe the case of a 35-year-old lady with a posterior mediastinal hydatid cyst who presented with progressive paraplegia. Excision of cyst was followed by systemic Albendazole therapy. She showed neurological recovery without recurrence till now. The role of Albendazole in preventing recurrence has been stressed and the relevant literature has been reviewed.

Adult↗
PubMed1989

Surgical pathology of mitral valves--the Indian scene.

Of the 75 cardiac valves excised at surgery over a 2 year period, 54 were mitral valves. Using simple morphological criteria along with clinical data, the valves were assigned to 2 major groups, rheumatic and non-rheumatic. The group with rheumatic disease accounted for 90% of cases. Mitral stenosis, incompetence and combined stenosis with incompetence were encountered with equal frequency (38, 38 and 24%). Mitral insufficiency of rheumatic etiology, no longer considered to be a major problem in the west, continues to be frequent in India. An increased incidence of mitral regurgitation in young females is an important feature noticed in this series.

Adolescent↗
PubMed1988

Intraosseous schwannoma of the cervical spine associated with skeletal fluorosis.

Intraosseous Schwannoma of the cervical spine is very rare. Its association with skeletal fluorosis is also extremely rare. A case of successfully treated intraosseous neurofibroma of the cervical spine associated with skeletal fluorosis causing tetraparesis is reported. The clinical features, diagnostic aspects and the management is described and the literature is reviewed.

Calcinosis↗
PubMed1985

Interaction of galactose and dietary protein deficiency on rat lens.

Protein deficiency, a frequently encountered nutritional disorder of developing countries is known to affect the proliferative and synthetic activities of several cell systems. But neither all the organs are affected at the same time nor at the same rate. The lens, which is an unique organ has been shown to suffer in protein malnutrition but without any clinically discernible changes. Clinical evidence suggests, early onset of senile cataract in underdeveloped countries is possibly due to protein deficiency. In the present investigation, it has been shown that addition of small concentrations of galactose to the diet readily induces cataracts in protein-deficient rats. This therefore supports the contention that protein deficiency alone may not produce morphological changes but exogenous or endogenous cataractogenic insults, may produce lenticular opacification in the protein-deficient state.

Animals↗
PubMed1983

Influence of undernutrition on the lenticular epithelium in neonatal and weanling albino rats.

Protein malnutrition, a morbid nutritional disorder of the developing countries, is known to interfere with cell replication. The influence of undernutrition on the lens which represents a unique combination of static, conditional renewal and constant cell renewal systems is not completely understood. In the present investigation it has been shown that undernutrition results in poor synthetic and proliferative activities of lenticular epithelium in neonatal and post-weaning rats. It is supposed that protein deficiency per se may not produce clinical diseases, but may increase the susceptibility of lenses to exogenous and/or endogenous insults.

Animals↗