Septic joint replacement: an orthopedic perspective.
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Biomedical subjects
Publications and source records attributed to K Saleh.
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The biology of nineteen taxa of African Stomoxyinae was studied during experiments with odour-baited Vavoua traps in Nairobi National Park, Kenya. Both male and female Stomoxys were captured in similar numbers with CO2 released at 2 l/min or octenol released at 2 mg/h. Some species of Haematobosca reacted synergistically to a combination of these attractants, producing large increases in catch. Stygeromyia and Rhinomusca responded only to CO2 and Prostomoxys did not respond to either bait. Many different activity patterns were documented in these genera, but most activity was concentrated just prior to sunset. For example, at peak densities nearly 1500 Stomoxyinae representing fourteen taxa were caught in a single trap between 18.00 and 19.00 hours. The Stomoxyinae community was exceptionally diverse when compared with other biting fly communities. Using data from traps set with different odour baits in the park forest, Shannon-Wiener diversity indices (H') varied from 2.5 to 2.8, and evenness (J') varied between 0.61 and 0.68. The Stomoxys population was extremely female-biased at the start of the rainy season, with species such as S. inornatus and S. boueti consisting of nearly 100% females. Sex ratios equalized when the first rainy-season generation emerged. population doubling times estimated from trap indices were approximately 12-16 days in two habitats (forest and riverine woodland).
Thirteen patients with generalized synovial chondromatosis of the knee were treated by either removal of the loose bodies alone (n = 5) or arthroscopic synovectomy (n = 8). The average follow-up was 38 months (range 23-61). There were three recurrences in the loose body removal group, which were subsequently treated by arthroscopic synovectomy. Statistical analysis of the results shows a significant improvement in pain, synovitis and effusion, range of movement, and function after either treatment. The group treated by arthroscopic synovectomy had significantly lower recurrence rates (p = 0.02). We recommend arthroscopic synovectomy for patients with generalized synovial chondromatosis. However, if loose bodies alone are removed, a recurrence can be successfully treated by an arthroscopic synovectomy.
Colony-forming cells (CFC) and colony-stimulating activity (CSA) in peripheral blood cells have been studied before and repeatedly during treatment of 32 patients with acute myelogenous leukemia. WBC obtained after Isopaque-dextran separation were cultured in vitro by a double-layer agar technique. Before treatment 19 patients out of 32 had CSA and all had CFC; both CSA and CFC were found in 19 patients. In follow-up studies during treatment, CSA was mainly unaffected during the leukopenic phase, while CFC were suppressed. No CFC were found at WBC counts below 1,000/mm3. This seems to imply that CFC are more sensitive to chemotherapy than colony-stimulating cells. 14 patients entered remission; all of them had CSA. 16 out of the 18 nonresponders lacked on or both types of cells. The presence of CSA and CFC in peripheral blood therefore appears to be a sign of favorable prognosis, while the absence of CSA and/or CFC implies lack of response to treatment. The conclusion from this study is that the presence of both CFC and CSA in peripheral WBC is a sign of a good prognosis. Absence of CFC and/or CSA in the initial sample indicates that the patient is unlikely to respond to conventional therapy with cytotoxic drugs. The presence or absence of CSA alone has a higher prognostic significance than the presence or absence of CFC.
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