[Alveolar proteinosis:disease, syndrome or tissue reaction?].
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Biomedical subjects
Publications and source records attributed to K Salfelder.
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In a 3-year-old boy disseminated histoplasmosis was recognized from a liver biopsy. The patient died shortly afterwards and had foci of the disease in liver, spleen, and kidneys. Large numbers of yeast cells of Histoplasma capsulatum were found within histiocytes in other organs including the eye. This rare finding is remarkable in view of the search for Histoplasma capsulatum in the syndrome known as "so-called histoplasmosis of the choroid."
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Pulmonary alveolar proteinosis (PAP), in addition to acute generalized histoplasmosis, was found at autopsy of three adult males, 23, 51, and 52 years of age. All three patients became ill in the same region of Venezuela, south of Lake Maracaibo, an area considered highly endemic for histoplasmosis. The PAP may be due to an environmental factor.
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A symmetrical deforming cutaneous sporotrichosis with verrucous lesions on both hands and of long clinical duration is reported. The difficulties in making an etiological diagnosis are considered.
Two cases of pseudotumoral eosinophilic ileocolitis are described. Apparently there are two forms: the first produced by nematodes with vasculitis and the other one produced by microfilaria with eosinophilic granulomatas. Similar observations are published in Costa Rica. Clinical importance, location and differential are discussed.