A clearer understanding of the aetiology of periodontal diseases can only be gained by further studies on the effects of plaques on the organism. Furthermore, the pathogenic plaque components must be assessed. It seems worth while maintaining the working hypothesis that periodontal disease is a plaque-induced clinical picture and that its various types are due to variations in the power of resistance of the organism. The better understanding of this changed reactivity and of the pathogenic plaque components must be aimed at.

Cell Migration Inhibition↗

PubMed1977

[Isolation of adenovirus from circulating lymphocytes in recurrent aphthae].

Explore the source record for details and available documents.

Adult↗

PubMed1977

[Stomatitis migrans].

Explore the source record for details and available documents.

Adult↗

PubMed1976

[Thermographic studies in mouth diseases and dental diagnosis].

Explore the source record for details and available documents.

Diagnosis, Oral↗

PubMed1976

[Pathomechanism and surgical treatment of periodontitis].

Explore the source record for details and available documents.

Humans↗

PubMed1975

[Etiology and prevention of recurring aphthous stomatitis].

New results concerning the etiology of recurrent aphthae are reported. According to own experiments of the authors, adenoviruses persisting in the epithelial cells of the oral mucosa may sensitize the aphthous patient. Adenovirus antigen was demonstrable in the oral mucosa cells in more than 50% of the patients and in the lymphocytes in approx. 1% of the patients. Lymphoblast transformation in the circulating lymphocytes could be demonstrated in vitro with heat-inactivated type 1 adenovirus, in 75% of the patients. This virus type has been isolated from 2 patients. Köbner's isomorphous phenomenon could be demonstrated in aphthous patients. The use of a disinfectant for mouth rinsing, the removal of foci as well as vitamin treatment are recommended for preventing recurrent aphthae.

Adenoviridae Infections↗