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Biomedical subjects

K Sarangapani

Publications and source records attributed to K Sarangapani.

6 recordsLinked to original sources

Malignant transformation in congenital sebaceous naevi in childhood.

Sebaceous naevi are uncommon congenital skin lesions with a well-recognised potential for neoplastic change. They should be considered premalignant lesions as malignant degeneration, most commonly basal cell carcinoma and squamous cell carcinoma, occurs with a lifetime risk of between 5% and 22%. This incidence is equal to that of actinic keratosis and exceeds that of oral leukoplakia. Such change, however, is rare before puberty. Basal cell carcinoma may develop in children with naevoid basal cell carcinoma syndrome, xeroderma pigmentosum and rarely de novo but sebaceous naevus is the only solitary lesion in childhood associated with the development of basal cell carcinoma. We present two cases of malignant transformation in a congenital sebaceous naevus occurring in childhood and review the literature and discuss the evidence upon which to base management guidelines.

Biopsy, Needle↗

Neurilemmoma of deep branch of ulnar nerve presenting as ulnar tunnel syndrome.

A rare case of neurilemmoma of the deep branch of the ulnar nerve presented as ulnar nerve compression syndrome. This tumour was arising from the deep branch at the wrist just distal to the ulnar tunnel. By its proximity to the sensory division, it led to sensory symptoms in the ulnar two digits. Certain features of this case, which are uncommon are discussed.

Diagnosis, Differential↗

Multiple cystic adenomas of labial salivary glands.

A case of multiple cystic adenomas is described and their histological characteristics discussed. Review of the literature showed no previous publication of multiple tumours from labial salivary glands.

Adenoma↗

Cut palmaris longus tendon--to repair or not to repair?

It is suggested in certain circumstances, that a divided palmaris longus tendon should be repaired, as it is an ideal choice for a tendon graft, or could be of use as a tendon transfer. The musculotendinous unit may be of use as an autogenous free graft.

Humans↗