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Biomedical subjects

K Sardana

Publications and source records attributed to K Sardana.

At least 19 recordsLinked to original sources
PubMed2006

Classic Kaposi's sarcoma in a Nepalese woman from a purportedly nonendemic area.

Kaposis sarcoma (KS) occurs as four types; classic, endemic, immunosuppression-associated, and AIDS-associated. The presence of KS-associated herpesvirus (human herpesvirus 8) DNA in the tissue samples of 95% of all variants of KS has confirmed its role in the aetiopathogenesis of KS. It is now believed that these clinical variants most likely represent different manifestations of the same pathological process. Our case represents the first case of classic KS from our region.

Aged↗
PubMed2004

Giant combined dermatofibroma with satellitosis.

An unusual giant combined dermatofibroma is reported in a 34-year-old man who presented with skin-coloured swellings on the medial aspect of the left scapula. The plaque was well defined, reddish-brown and 25-30 cm in diameter. It was also tender and indurated. Several similar smaller lesions (satellites) were present around the plaque. Light microscopy of an incisional biopsy from the main lesion showed architectural features of a deep penetrating type of dermatofibroma, with xanthomatous aggregates, myxoid changes and probable myofibroblastic differentiation. Our case represents an extraordinary example of giant combined dermatofibroma with satellitosis. Despite its benign nature, a wide excision is contemplated because of its unsightly appearance and physical discomfort.

Adult↗
PubMed2001

Tuberculosis of the vulva masquerading as a sexually transmitted disease.

Tuberculosis of the vulva is a rare condition usually seen by a gynecologist. We report a case of chronic ulcer on the vulva of four months duration, which, on detailed investigation, turned out to be a case of primary inoculation tuberculosis. The patient was subsequently put on antitubercular therapy with a good the therapeutic response. The rarity of this presentation in dermato-venereology is emphasized.

Adult↗
PubMed2001

Linear and whorled nevoid hypermelanosis.

Linear and whorled nevoid hypermelanosis (LWNHM) is a reticulate pigmentary disorder with a sporadic occurrence, representing genetic mosaicism. It is characterised by hyperpigmented macules in a reticulate pattern along Blaschko's lines, sparing the mucous membranes and stabilising after one to two years. It may be associated with various neurological abnormalities. The disorder may resemble incontinentia pigmenti, epidermal nevus, or zebra-like hyperpigmentation clinically. We report LWMNHM in a 15-year-old girl with progressively increasing streaks of reticulate hyperpigmented macules arranged in a whorled pattern over the trunk and extremities, which appeared soon after birth. There was no history of any preceding eruption or any associated systemic abnormality. Histopathological examination revealed basal cell hyperpigmentation without any pigmentary incontinence. CT scan of the brain was normal.

Abdomen↗
PubMed2001

A suspected case of primary cutaneous actinomycosis on the buttock.

Primary cutaneous actinomycosis is rare and can mimic mycetoma, tuberculosis and nocardiosis. The results of cultures (aerobic and anaerobic) are not always positive. A high degree of clinical suspicion should be entertained and a combination regimen of penicillins with sulphonamides should be used for treatment. We report a patient with primary cutaneous actinomycosis over the buttock, who was successfully treated with amoxicillin and sulphonamides.

Actinomycosis↗