[A case of inflammatory fibroid polyp of the ileum].
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Aged↗
Biomedical subjects
K Satou
Publications and source records attributed to K Satou.
[Calcitonin values in normal human blood].
Since 1969 when Clark, et al. established the radioimmunoassay for human calcitonin, a number of reports have been published. However, the normal value of calcitonin has never been definitely ascertained. The calcitonin value in the blood of 256 normal individuals was measured by radioimmunoassay using the Dai-ichi Calcitonin Kit, and the X-ray findings in 133 of this population were studied. The calcitonin value was found to range from less than 10 to 249 (average 49.0) pg/ml. In terms of age, it was shown to be highest in the third decade and tended to decrease from the fourth decade on. In terms of sex, it was higher in females in the second, sixth and seventh decades but higher in males in the third--the fifth decades. There was no relationship between the degree of bone atrophy and the calcitonin value in the blood.
Adult↗
Hemagglutination with rhabdoviruses related to bovine ephemeral fever virus.
Three different bovine ephemeral fever group viruses were tested for hemagglutination (HA). One of them, Tortilla Flat virus (CSIRO 368), agglutinated erythrocytes from geese, pigeons, horses, hamsters, mice and guinea-pigs when the concentrated infectious culture fluid was used as a hemagglutinin. The HA was dependent on the pH of phosphate buffered saline used as the erythrocyte diluent when using borate buffered saline (pH 9.0) with 0.4% bovine serum albumin as the antigen diluent. The optimal pH of the phosphate buffer was from 5.2 to 5.8. The HA, however, was not dependent on salt concentration. The incubation temperature did not affect the HA titer significantly. This HA reaction was inhibited by serotype specific antiserum.
Animals↗
[A chemotherapy regimen including CDDP in patients with bronchogenic carcinoma--a comparison between bronchial artery infusion and intravenous administration].
Forty patients with lung cancer were treated using two methods. One was transbronchial artery infusion (BAI) of CDDP and the other was intravenous administration of CDDP with VDS, ACNU or etoposide. There was no difference in response rate between the two groups. The response rate was higher in patients with squamous cell carcinoma compared to these with adenocarcinoma. Compared with the combination group, BAI patients had fewer adverse effects, such as myelosuppression, alopecia, nausea and vomiting. Thus, it was concluded that CDDP is very effective for patients with lung cancer and that CDDP administered by BAI is useful for hilar-type squamous cell carcinoma.
Aged↗
[Minimal-flow xenon and semiclosed circuit anesthesia for computed tomographic measurement of local cerebral blood flow (LCBF)].
For the purpose of decreasing the volume of expensive xenon, anesthesia with minimal-flow xenon and semiclosed circuit were induced for computed tomographic LCBF measurement. Eighteen patients with ischemic cerebral disease were studied. Anesthesia was induced with minimum dose of thiopental, diazepam and fentanyl. Muscle relaxation was obtained by means of pancuronium bromide. Patients were intubated and ventilated mechanically with flows of 6 l/min. O2 for 20 to 30 minutes to eliminate nitrogen from the system. O2 concentrations in semiclosed circuit were monitored throughout the procedures using galvanic battery. Endtidal CO2 tension was also measured for maintaining normocarbia. Blood gas analyses were carried out before xenon inhalation, during xenon inhalation and immediately before stopping inhalation of xenon-oxygen mixture. Xenon inhalation programs were subdivided into three groups, each of them consisted of 6 patients. The formula for calculating fresh gas flow for low flow semiclosed circuit was introduced according to Shimoji's which was based on the original formula of Foldes. O2 concentration in circuit was predicted to be 25%. Mean xenon uptake for initial 20 minutes was predicted to be 125 ml/min. or 360 ml/min. (Formula: see text) (CRO2: O2% in semiclosed circuit. FO2: fresh O2 flow ml/min. FXe: fresh xenon flow ml/min. VO2: oxygen consumption ml/min. VXe: mean xenon uptake ml/min.) The first group started xenon inhalation during pure xenon inflow into semiclosed circuit for two minutes and followed by about 68% xenon in O2 inhalation for 23 minutes. FXe and VXe were fixed at 700 ml/min and 360 ml/min respectively.(ABSTRACT TRUNCATED AT 250 WORDS)
Adult↗
Characteristics of hepatocytes derived from early ES cells and treatment of surgically induced liver failure rats by transplantation.
BACKGROUND: Although liver transplantation has become a standard therapy for diseases such as fulminant hepatitis and cirrhosis, the lack of donor organs remains a major problem. One solution is the development of transplantable hepatocytes. The metabolic characteristics as well as function and adaptation of hepatocytes (R-EES-hep cell) derived from rat early embryonic stem cells were examined after transplantation into rats with surgically induced liver failure. METHODS: Rat hepatocyte cell lines were established from early embryonic stem cells cultured in the presence of embryotrophic factors by colony cloning methods. The cell lines were established from two cell embryos taken from spontaneous dwarf rats using the novel method of Ishiwata et al. Morphologic differentiation as well as albumin and bilirubin production were observed by immunostaining. R-EES-hep cells were transplanted into the spleens of 90% hepatectomized, surgically induced liver failure rats to analyze survival rates. RESULTS: When cultured in type I collagen gel the cells formed cordlike structures resembling the liver. Both albumin and bilirubin production were observed when transplanted; the spleen was converted into a liver-like structure with prolonged survival of the 90% hepatectomized rats for up to 3 months up to the time of killing. CONCLUSIONS: R-EES-hep cells showed many of the distinctive metabolic characteristics of the liver. These cells may be efficient for further research and application for hepatic cell transplantation to treat liver insufficiency patients and as biologic artificial organs.
Animals↗
Esophageal reconstruction using a stomach roll following endoscopic mucosal resection.
A 73-year-old male patient presenting with synchronous triple cancer of the hypopharynx, esophagus and stomach is herein reported. To pursue safety by reducing surgical stress and better postoperative quality of life, we preserved the stomach by treating the gastric cancer by endoscopic mucosal resection and subsequently used the stomach for making an elongated stomach roll during the esophageal reconstruction. Postoperatively, no complications occurred and the patient has been on oral feeding for 23 months with no recurrence of primary cancer.
Adenocarcinoma↗