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Biomedical subjects

K Shinada

Publications and source records attributed to K Shinada.

10 recordsLinked to original sources

Psychological well-being and perceptions of stress amongst Japanese dental students.

The purpose of this study was to investigate the relationship between Psychological General Well Being (PGWB) and perceived sources of stress amongst dental students in Japan. Second to sixth year dental students of Tokyo Medical and Dental University were invited to participate in the questionnaire survey. The questionnaire collected information on demographic and social background, lifestyle behaviours, the PGWB index and the Dental Environment Stress (DES) questionnaire. A total of 320 students (56% male) participated, with a response rate of 91%. Male students had significantly higher PGWB scores and lower DES scores than female students (P < 0.05). There were no significant differences in the year of study for DES mean score and PGWB total score. Students whose first choice of admission was dentistry experienced less stress than those whose first choice was another discipline (P < 0.05). Students who regularly exercised showed significantly lower stress levels and higher well-being status than those students who did not exercise (P < 0.01). Correlational analysis showed an inverse relationship between PGWB and DES scores (r = -0.544, P < 0.001). Multiple regression analysis revealed that DES mean score was significantly related to gender, first choice of admission and PGWB total score. It is suggested that perception of stress amongst Japanese dental students is influenced by gender, dentistry as first choice for admission and students' general well-being.

Adult↗

[Statistical analysis of a dental care program for homebound elderly patients in Shinjuku-ku].

A dental care service program for homebound elderly patients has been operating since 1988 in Shinjuku-ku, Tokyo. The purpose of this study was to clarify the characteristics of patients who received this dental care service. Based on a survey questionnaire and treatment card from April 1995 to March 1999, we analyzed the characteristics of patients. The following conclusions were obtained. 1. We studied 301 patients (males, 124; females, 177). The average age of the patients was 81.2 +/- 9.0 years. Eighty-four percent of the patients had a medical history. 2. Oral hygiene was practiced by 68% of the subjects: 78% by themselves, and 22% by caregivers. Half of the patients (53%) brushed their teeth every day, and one-third (32%) did not. 3. The mean number of DMF teeth was 25.4 (DT, 1.6; MT, 20.5; FT, 3.3). 4. About eighty percent (79%) of the patients had removable dentures, and one-third of them were upper and lower complete dentures. 5. The chief complaint of homebound elderly was the denture problem (73%). Therefore, the care provided at the bedside was mainly denture-related treatments. 6. Average times for visiting were 5.1. 7. Sixty-eight percent of the patients requested home dentist's visitation for dental care service, and 80% of the requested dentists performed such treatment. 8. Seventy-eight percent of the elderly patients were satisfied with the service program. This dental care program for homebound elderly patients seemed to work well. However, to meet needs for the expanding number of aged persons and to make it coincide with the new health and welfare scheme, reform of the program might be necessary.

Aged↗

[Questionnaire on "having a family dentist" and the status of oral health].

In 1999, we gave a Questionnaire on "having a family dentist" to 414 workers (300 males, 114 females) at a government office. Oral health examination was also provided to the same subjects. The following results were obtained: 1. Female workers (43%) had a family dentist more often than male workers (29%), and the difference was significant (p < 0.01). 2. About 45% of the subjects received regular dental checkups at least once a year; however, half of them did not have a family dentist. 3. Convenience, comfort, and communication factors were the main reasons for choosing a particular dentist, while continuity, comprehensiveness, and specialty factors were not taken into consideration in choosing a dentist. 4. The persons who had family dentists had more FT and DMFT, and fewer total numbers of teeth than those without family dentists. From these results, it was suggested that people visited dentists with dental problems and received treatment repeatedly, and then they came to have family dentists. The habit of visiting a dentist regularly seeking checkups and prevention is not yet popular among Japanese adults. To improve oral health consciousness and to promote oral health, it should be recommended to receive regular checkups and oral health education by a family dentist. However, the present condition does not allow this system. Therefore in Japan, it should be encouraged to provide oral health examination and oral health education regularly at work sites, to improve the oral health of the adult population.

Adult↗

Evaluation of school-based dental health activities including fluoride mouth-rinsing in Hiraizumi, Japan.

School-based dental health activities conducted in Hiraizumi over the past 20 years have remarkably improved the dental health status of schoolchildren. For example, DMFT index of 12-year-old children decreased to 1.5 in 1998, one-half that of the national average. School dental health activities, which were focused on dental health education, resulted in an increase of filled teeth rates, a decrease in the number of missing teeth, and a decline in incisor caries (1979-1986). In addition, the introduction of a school-based fluoride mouth-rinsing program (1986 - ) showed a positive effect on the prevention of dental caries; a significant decrease was observed in the overall prevalence of dental caries, particularly in the molars. In Japan it seems advantageous to promote the dental health of schoolchildren by school-based programs that combine dental health examination, dental health education and fluoride mouth-rinsing program. Especially, to prevent dental caries in the mandibular first molars more effectively, it is recommended to start fluoride mouth-rinsing at age 5.

Adolescent↗

[Study on oral health status and health behavior of workers at government office].

The purpose of this study was to investigate the oral health status and health behavior of the adult population in the workplace. In 1998, oral health examination of 388 workers (male: 287, female: 101) at a government office was performed. A questionnaire was administered to obtain data regarding oral symptoms and health behavior. The results were as follows: Overall, 48% needed treatment for dental caries, 44% needed calculus removal, and 23% needed treatment for periodontal disease. Although there were no oral health complaints, 20% had early caries, 40% had dental calculus, and 19% had periodontitis. Compared to males, more females brushed their teeth, had home dentists (44%) and received more regular dental health check-ups at least once a year (48%). For males, those with home dentists had higher FT and DMFT in the twenties and thirties. There was no relationship between oral health status and regular check-ups in both males and females. The results revealed that receiving regular dental check-ups from home dentists was not popular in Japan. Further, the role of home dentists is not preventive oriented. It was concluded that it is necessary to provide regular oral health examination and health promotion programs for adult population at the workplace in Japan.

Adult↗

Regioselective syntheses of sulfated polysaccharides: specific anti-HIV-1 activity of novel chitin sulfates.

A novel and convenient method for the regioselective syntheses of sulfated analogs of chitin and chitosan is described in relation to studies on structure-biological activity. Fully protected, soluble derivatives of chitosan were found to be useful intermediates for the syntheses of a novel class of sulfated polysaccharides, 2-acetamido-2-deoxy-3-O-sulfo-(1-->4)-beta-D-glucopyranan (3-sulfate, 3S, 4) and (1-->4)-2-deoxy-2-sulfoamido-3-O-sulfo-(1-->4)-beta-D-glucopyranan (2,3-disulfate, 23-S, 3). These compounds were tested for their activities in (i) inhibiting HIV-1 replication in vitro and (ii) inhibiting blood coagulation. The results reveal that the selective sulfation at O-2 and/or O-3 affords potent antiretroviral agents showing a much higher inhibitory effect on the infection of AIDS virus in vitro than that by the known 6-O-sulfated derivative (6-sulfate, 6S). Moreover, the 23-S product completely inhibited the infection of AIDS virus to T lymphocytes at concentrations as low as 0.28 microgram/mL without significant cytotoxicity. The regioselective introduction of sulfate group(s) at O-2 and/or O-3 had little effect on generating anticoagulant activity, whereas 6-O-sulfated chitin strongly inhibits blood coagulation. These results suggest that the specific interaction of these new types of chitin sulfates with gp 120 of the AIDS virus depends significantly on the sites of sulfation rather than on the total degree of substitution on sugar residues.

Animals↗

[A longitudinal cohort study on the relation between physical condition and masticatory ability in the elderly].

The present study was conducted to determine the relation between physical condition and masticatory ability. The subjects were residents over 65 years old living in three different areas in Sagae City. The physical conditions assessed were height, weight, rate of body fat, grip strength, and bone mineral density. Masticatory ability was evaluated by the test jelly method. The results were as follows: 1) There was a difference in physical condition among subjects from the three residential areas. 2) For males, the group who maintained their masticatory ability exhibited better physical condition than those who did not. As for females, however, the physical condition was more strongly affected by age than masticatory ability.

Aged↗

[Distribution of Candida species and mutans streptococci related to oral conditions in elderly persons].

The purpose of this investigation was to find the relationship between the occurrence of Candida species and mutans streptococci at 7 sites (saliva, tongue, mucosa, teeth, clasp, external, and mucosal denture surfaces) in the mouth of 97 elderly persons (males: 43, age: 76.4 +/- 6.7 years; females: 54, age: 75.0 +/- 6.6 years). Among the subjects, there were complete denture wearers (n = 20), partial denture wearers (n = 45), and non-denture wearers (n = 32). Candida species were more significantly (p < 0.001) predominant in complete and partial denture wearers (80% each) than in non-denture (18.8%) wearers. The presence of Candida was highest on the mucosal denture surfaces followed by clasp, tongue, and remaining teeth in that order. Positive correlation were significantly found between the CFU numbers of Candida species and mutans streptococci present on the external surfaces (p < 0.001), natural teeth (p < 0.001), clasp (p < 0.01), and saliva (p < 0.05). A negative correlation (r = -0.503; p < 0.001) was found between the number of teeth and the CFU numbers of Candida species. Moreover, the CFU numbers of both groups of microorganisms also increased in 80-year-old and over persons. Candida species were most predominantly found in persons with poor oral and denture cleanliness.

Age Factors↗

[A morphological study of interactions of Candida albicans and Streptococcus mutans].

Denture stomatitis is caused mainly by infection of Candida albicans and Streptococcus mutans, the most predominant members of the bacterial flora on denture surfaces. The purpose of this study was to investigate the adhesion in vitro of C. albicans and of S. mutans to acrylic surfaces and their interactions. Concentrations of C. albicans and of S. mutans (mutational phase I and III in which activities of glucosyltransferases are higher and lower respectively) were of high levels (> or = 5.0 x 107 colony-forming-units per ml; CFU/ml). The colonies in brain-heart-infusion (BHI) broth added 5% sucrose incubated at 37 degrees C for 18 and 72 hours. Then the samples were dried and evaporated, and examined by S-700 and S-4100 SEM (HITACHI). It was found that S. mutans (mutational phase I) synthesized water-insoluble glucans concomitantly with the adhesion of both S. mutans and C. albicans to the acrylic surfaces. Also, adhesion of C. albicans, mediated by cell-to-cell interactions with S. mutans (especially mutational phase III), to the surfaces was observed.

Acrylic Resins↗

[A comparative study of five indices in malocclusion for evaluating treatment needs].

The purpose of this study was to investigate the utility of five indices of malocclusion (NMT, MI, HLDI, OFI and DI) for evaluating the necessity of orthodontic treatment. One dentist scored malocclusion in 40 females (Age: 18-23). Then, another orthodontist assessed the treatment needs for malocclusion on the same subjects. We compared each score with the assessment by the orthodontist and determined the screening level score of the treatment needs for malocclusion. The sensitivity and specificity were calculated for 5 indices respectively. The selection using MI (screening level score: 12) resembled mostly the assessment by the orthodontist, followed by NMT (screening level score: 8) and DI (screening level score: 8). But the time required to score using MI was longer than using DI, and the reproducibility of NMT was inferior to DI. The subjects in this study had a high frequency of crowding (22.5%), and DI was highly correlated to the arch length discrepancy (r = -0.898). From these results, it was suggested that DI was a suitable index for evaluating the treatment needs for malocclusion, particularly crowding.

Adolescent↗